HHV-8-Related Lung Neoplastic and Nonneoplastic Diseases
Fig. 20.1 Skin. KS showing epidermis on the left and proliferation of spindle cells with many vascular channels and mild inflammatory reaction on the mid and right side of the…
Herpesvirus
Fig. 6.1 Herpesvirus-1 ×7500 (Courtesy M. Selig) 6.4 Immunology Herpesvirus types 1 and 2 can both infect the lung (Ramsey et al. 1982). HSV-1 is the most frequent cause of…
Influenza Virus
Fig. 9.1 Neuraminidase and hemagglutinin expression of the influenza virus correlates with epidemic outbreaks Although its precise provenance is uncertain, the recent epidemic of Novel H1N1 Influenza/2009 started as an…
Coronavirus
Fig. 13.1 Artist illustration of the club-shaped surface projections (peplomers) that give coronaviruses their unique coronal fringe by negative-staining electron microscopy (Illustration by Adrian Galvin, New York, NY) Fig. 13.2…
Viral Hemorrhagic Fevers
Virus family Genus Virus Disease Vector Geographicdistribution Case fatalityrate (%) Flaviviridae Flavivirus Yellow fever Yellow fever Mosquito Tropics, Africa, and South America 20 Dengue Dengue hemorrhagic fever Mosquito Throughoutthe tropics…
Herpesvirus-4/Epstein-Barr Virus (EBV)
Fig. 21.1 EBV pneumonitis shows dense pulmonary perivascular and interstitial infiltrates 21.8 Lymphomatoid Granulomatosis Lymphomatoid granulomatosis was first described by Liebow and colleagues in 1972 as an angiocentric and angiodestructive…
Cytomegalovirus
Histopathology (1) Cytomegaly (2) Eosinophilic intranuclear Cowdry type B inclusions resembling an “owl’s eye” (3) Amphophilic intracytoplasmic inclusions Differential diagnosis Herpes simplex Varicella zoster Adenovirus Measles Reactive pneumocytes Radiographic findings…
Parainfluenza Virus
Fig. 10.1 Lung biopsy with parainfluenza infection. (a) Acute and organizing pneumonia with bronchiolitis and multiple multinucleated giant cells consistent with infection by parainfluenza virus. (b, c) Multinucleated giant cell…
