CHAPTER
5
Accessory Pathways
UNDERSTANDING AND EVALUATING ACCESSORY PATHWAYS (APs)
General Information
The ventricles are normally insulated from the atria by a fibrofatty connective tissue skeleton that also contains the valvular structures.
○In certain cases, an extranodal bypass tract (or accessory pathway, AP) connects the atrial and ventricular myocardium across the atrioventricular (AV) groove, bypassing the atrioventricular node (AVN).
○Such an AP allows for electrical activation of the ventricular myocardium before the impulse arrives via the AVN/His-Purkinje conduction system, causing pre-excitation.
Anatomy and Pathophysiology
Most APs have rapid, non-decremental conduction similar to myocardium or His-Purkinje tissue.
○ Bidirectional conduction is present in most bypass tracts.
▪ Bidirectional conduction could result in orthodromic or antidromic atrioventricular reciprocating tachycardia (AVRT) and pre-excited atrial arrhythmias/atrial fibrillation (AF).
○ Anterograde conduction could result in antidromic AVRT and pre-excited atrial arrhythmias/AF. It can be:
▪ Manifest: Anterograde conduction down AP results in pre-excitation on electrocardiogram (ECG).
▪ Latent: Anterograde activation is not manifest due to relatively greater degree of AVN conduction. The relative balance of AVN and AP conduction is dependent on:
• AVN conduction velocity (vagal maneuvers, premature atrial complexes [PAC], and adenosine increase pre-excitation by decreasing AV conduction)
• AP conduction velocity (increased pre-excitation with rapid conduction)
• The proximity of the bypass tract to the atrial impulse; for example, a sinus node impulse reaches the AVN or a right-sided AP earlier than it would a left-sided AP.
▪ Intermittent: Suggests a relatively long anterograde effective refractory period (ERP)
○ Retrograde: Exclusive retrogradely conducting pathways are called concealed APs.
▪ No delta wave is seen due to lack of anterograde activation.
▪ Orthodromic AVRT is possible, but pre-excited atrial arrhythmias/AF cannot occur.
Types of APs
○ Atrioventricular (bundle of Kent; Wolff-Parkinson-White syndrome [WPW])
▪ Bypass tract along the AV groove connects atrial and ventricular myocardium (bypassing the AVN/His-Purkinje system).
▪ ECG: Short PR interval with wide QRS/delta wave (if manifest)
▪ Electrophysiology study (EPS): Short HV interval (if manifest)
○ Atrionodal (James fibers; Lown-Ganong-Levine syndrome)
▪ Bypass tract connects the atrium to the distal compact AVN.
▪ ECG: Short PR interval with normal QRS
▪ EPS: Short AH interval
○ Intranodal (James fibers; Lown-Ganong-Levine syndrome)
▪ Specialized fibers in node
▪ ECG: Short PR interval with normal QRS
▪ EPS: Short AH interval
○ Atriohisian (Brechenmacher fibers; Lown-Ganong-Levine syndrome)
▪ Bypass tract connects the atrium to the His bundle
▪ ECG: Short PR interval with normal QRS