Fig. 1.1. Scanning electron micrograph of C. albicans growing on oral epithelial cell layer, in yeast, hyphal and pseudohyphal morphologies. Hyphae invade via active penetration and induce endocytosis, indicated by…
Fig. 7.1. Molecular mechanisms of detection avoidance during interaction of Histoplasma yeasts with macrophages. Adherence and phagocytosis of yeasts into macrophages is mediated by cell-wall-localized Hsp60 binding to CD18-family receptors…
Fig. 9.1. Clinical presentation of oral C. albicans infections with erythematous patches and white pseudomembranes on the tongue of a patient with chronic mucocutaneous candidosis C. albicans interacts with epithelial…
Fig. 5.1 (a) ASM model highlighting main components of the encoding of a force response by [Ca2+]cyt where propagating [Ca2+]cyt oscillations give rise to a sustained force response. (b) Demonstration…
Target Action/result Complex I ↓ Oxidative phosphorylation → ↓ ATP production ↑ ROS Complex III ↓ Oxidative phosphorylation → ↓ ATP production ↑ ROS Complex IV ↓ Oxidative phosphorylation → ↓ ATP production ↑ ROS Complex…
Fig. 8.1 Mitochondria as oxygen sensor. Mitochondrial reactive oxygen species generation at complex III of the respiratory chain. IMS intermembrane space, SOD superoxide dismutase Mitochondria in Cancer One constitutive metabolic…
Fig. 3.1 Schematic diagram of human mitochondrial genome to show the mtDNA-derived 13 polypeptides, 22 tRNAs (each was named based on respective amino acid), and two rRNAs (12S and 16S)….
Fig. 4.1 Proposed mechanism of blood pressure elevation in patients with OSA Effects of Continuous Positive Airway Pressure (CPAP) on Arterial Hypertension in OSA Patients In OSA patients, nasal CPAP…
Fig. 1.1 Pathway and sites of mitochondrial oxidative phosphorylation and ROS formation. Molecular oxygen is activated at complexes I, II, and III to superoxide anion (O2.−) in the mitochondrial inner…
Fig. 2.1 Regulation of mitophagy and autophagy. Schematic summarizes the p62/SQSTM1-regulated formation of autophagosome for recycling the damaged mitochondria and misfolded and aggregated proteins. Autophagy and mitophagy proceed through several…
