Upper Extremity Revascularization



Upper Extremity Revascularization



Cheong J. Lee and William H. Pearce


Symptomatic arterial disease of the upper extremity is uncommon, accounting for approximately 5% of all cases of extremity ischemia. Ischemia in the upper extremity is caused by a wide variety of diseases, many of which are both nonatherosclerotic and systemic in nature. Occupational, pharmacologic, medical, and athletic factors contribute to many of these diseases. Manifestations of arm ischemia include Raynaud’s phenomenon, pain, and claudication. Embolic symptoms include fingertip gangrene, petechiae, splinter hemorrhages of the nail bed, and livedo reticularis.


The most common symptom of upper extremity ischemia is Raynaud’s phenomenon (RP). Patients with RP experience episodic digital ischemia occurring in response to external stimuli including cold and occasionally emotional stress. Patients with RP may be subdivided into two distinct pathophysiologic groups, vasospastic and obstructive, based on the absence or presence of arterial occlusive disease. RP should be distinguished from Raynaud’s disease (RD), a primary vasospastic condition without a clear etiology. Other causes of upper extremity ischemia include additional forms of vasospasm induced by agents such as ergotomine, vasopressors, β-blockers, and cocaine (Box 1). A number of other causes of compromised upper extremity arterial circulation, including thoracic outlet syndrome, trauma, and a variety of arteritides, are discussed in detail In other chapters.



BOX 1   Causes of Upper Extremity Ischemia



Medical Conditions




Thromboembolism


Atherosclerosis


Atheromatous embolization


Connective tissue disease


Scleroderma


CREST syndrome


Rheumatic arteritis


Systemic lupus erythematosus


Polymyositis or dermatomyositis


Mixed connective tissue disease


Large artery vasculitis


Takayasu’s disease


Giant cell arteritis


Small artery (and vein) vasculitis


Thromboangiitis obliterans


Blood dyscrasias


Cold agglutinins


Cryoglobulins and cryofibrinogenemia


Myeloproliferative diseases


Behçet’s syndrome


Antiphospholipid antibody syndrome


Thoracic outlet syndrome


Congenital arterial wall defects


Pseudoxanthoma elasticum


Ehlers–Danlos syndrome


Fibromuscular dysplasia


Iatrogenic injury


Arterial blood gas and pressure


Cardiac catheterization


Arteriography


Frostbite


Kidney transplantation and related surgery


Azotemic arteriopathy


Hemodialysis access


Radiation


Breast carcinoma


Hodgkin’s disease





Pharmacologic Agents



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Aug 25, 2016 | Posted by in CARDIOLOGY | Comments Off on Upper Extremity Revascularization

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