Non–Small Cell Carcinomas of the Lung
Epithelial neoplasms are by far the most common primary malignancies in the lung. Worldwide, lung cancer is the leading cause of illness and death in patients with neoplastic disease as…
Benign Tumors and Tumor-like Lesions of the Lung
A wide range of conditions may manifest as tumors or tumor-like lesions in the lung parenchyma. Although space limitations prevent the inclusion of every single clinical entity that may manifest…
Tumors of the Pleura
The pleura can be seeded by a wide spectrum of primary and metastatic tumoral conditions. Primary neoplasms affecting the pleura include epithelial, mesenchymal, and lymphoid neoplasms; of these categories, epithelial…
Lung Tumors Derived from Presumed Ectopic Tissues
Tumors derived from presumed ectopic tissue constitute a family of tumors that are rarely encountered as primary intrapulmonary neoplasms. This is a diverse group in terms of not only histology…
Biphasic Tumors of the Lung
Primary malignant biphasic tumors occurring in the lung parenchyma are rare, accounting for no more than 1% to 2% of all primary malignant tumors of the lung. The two most…
Neuroendocrine Tumors of the Lung
Neuroendocrine carcinomas constitute an important group of primary neoplasms in the lung. Although the gamut of primary lung tumors that may show neuroendocrine differentiation is rather complex, involving tumors not…
Lung Tumors of Uncertain Histogenesis
This chapter describes a group of lung tumors characterized by uncertain histogenesis and very rare occurrence. Despite current advances in immunohistochemistry and molecular biology, definitive conclusions regarding the cellular origins…
Mesenchymal Tumors of the Lung
Primary mesenchymal tumors of the lung, whether benign or malignant, are rare. Sarcomas with histopathologic features similar to those seen in soft tissues may arise in the bronchopulmonary region; thus,…
Lymphoproliferative Tumors of the Lung
Malignant primary lymphoproliferative tumors of the lung are rare and represent a small percentage of all primary malignant neoplasms of the lower respiratory tract. Much of the current knowledge regarding…
Handling and Grossing of Larger Cases
The correct procedures for handling resected tissue and preparing gross specimens for histologic evaluation of thoracic tumors are of great importance not only for diagnostic purposes but also for staging…
