Thoracic Key

Pulmonary Hypertension: Classification and General Histologic Features Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Definition Pulmonary hypertension is defined clinically as a mean pulmonary artery pressure of ≥25 mm…

Miscellaneous Iatrogenic Lung Disease: Extracorporeal Membrane Oxygenation, Hydrophilic Polymer Embolization, Therapeutic Microsphere Embolization Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Extracorporeal Membrane Oxygenation Technical Considerations First introduced for clinical…

Radiation-Induced Lung Injury Allen P. Burke, M.D. Joseph J. Maleszewksi, M.D. General Radiation-induced lung injury is clinically classified into acute radiation pneumonitis, chronic radiation pneumonitis (radiation fibrosis), and sporadic radiation…

Drug-Induced Lung Injury Allen P. Burke, M.D. Patterns of Lung Injury Associated with Drugs General Considerations The diagnosis of drug-induced lung injury is one of exclusion, as the histologic findings…

Miscellaneous Pneumoconioses Allen P. Burke, M.D. Background Pneumoconiosis is defined as a restrictive lung disease resulting from occupational inhalation of dust, usually inorganic particulates. It differs histologically and pathogenetically from…

Silicosis Marisa Dolhnikoff, M.D., Ph.D. Fabio R. Tavora, M.D., Ph.D. Definition Silicosis is a fibrotic pulmonary disease caused by the inhalation and deposition of crystalline silica particles.1 Incidental silicoanthracotic nodules…

Asbestos-Related Lung Disease Michael Lewin-Smith, M.B., B.S. Allen P. Burke, M.D. Types of Asbestos Asbestos is a group of silicates that are defined by the formation of very long, thin…

Lung Disease in Bone Marrow Transplant Patients Fabio R. Tavora, M.D., Ph.D. Allen P. Burke, M.D. Graft-Versus-Host Disease Incidence Graft-versus-host disease (GVHD) occurs in approximately one-third of patients with allogeneic…

Miscellaneous Pathologic Findings in Lung Allografts Anja C. Roden, M.D. Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Posttransplant Acute Lung Injury (Primary Graft Dysfunction) Primary graft dysfunction (PGD) is…

Chronic Lung Allograft Dysfunction (Obliterative Bronchiolitis, Chronic Vascular Rejection, and Restrictive Allograft Syndrome) Anja C. Roden, M.D. Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Chronic Lung Allograft Disease The…