Fig. 12.1 Targetable oncogenes in NSCLC: (a) preferentially or exclusively expressed by lung adenocarcinoma; (b) preferentially or exclusively expressed by lung squamous cell carcinoma In the present chapter we will…
(1) The Christie NHS Foundation Trust and Manchester University, Manchester, GB, UK ALK Rearranged NSCLC The anaplastic lymphoma kinase (ALK) gene was first discovered as a component of the…
Clinical definition of acquired resistance 1. Previous EGFR TKI 2. Presence of a typical sensitizing EGFR mutation, e.g., exon 19 deletion, exon 21 L858R mutation, exon 18 G719X, or exon…
© Springer International Publishing Switzerland 2015Solange Peters and Benjamin Besse (eds.)New Therapeutic Strategies in Lung Cancers10.1007/978-3-319-06062-0_3 3. Minimally Invasive Surgery for Early NSCLC Brian E. Louie1 and Eric Vallières2 (1) Division of Thoracic Surgery, Swedish Cancer Institute and…
Study Year # patients OS @ 2–3a (%) LC @ 2–3a (%) Nagata et al. [30] 2005 45 75 98 Baumann et al. [31] 2009 57 60 92 Fakiris et…
Fig. 1.1 Outstanding issues to be considered prior to the implementation of Lung cancer CT Screening (Adapted from Field et al. [49]) Lung Cancer Risk Prediction Models A number of…
