Tuberculosis
Abstract Tuberculosis, caused by Mycobacterium tuberculosis, is the leading infectious cause of death worldwide; it is characterized by unique clinical stages. Adults with contagious forms of tuberculosis transmit the organism…
The Epidemiology of Asthma
Abstract Epidemiology is the study of populations to discover modifiable factors that contribute to disease occurrence and natural history with a view to reducing disease burden through prevention. Asthma is…
New Concepts in Children’s Interstitial and Diffuse Lung Disease
Abstract Children with diffuse and interstitial lung disease (chILD) comprise a group of rare disorders with significant morbidity and mortality. Individually these disorders are rare but collectively they create a…
The Influence of Upper Airway Disease on the Lower Airway
Abstract Upper airway disease, including chronic rhinitis and rhinosinusitis, affect most children with asthma. Over the past two decades, our understanding of the connection between the nose, paranasal sinuses, and…
Modern Molecular Therapies for Application in Managing Childhood Asthma
Abstract Focus on drug development for asthma has been on development of immunomodulator therapies, with the hopes that they can eventually alter the natural course of asthma. This review focuses…
Severe Asthma
Abstract Most pediatric asthma is easily treated with low-dose inhaled corticosteroids, occasionally combined with a long-acting bronchodilator, provided the medications are administered regularly and correctly. If the child does not…
Pulmonary Edema
Abstract Improvements in the intensive care and monitoring of patients with serious illnesses led to a greater appreciation of the significance of fluid movement into the lung as a complication…
Asthma in the Preschool Age Child
Abstract Wheeze in preschool children (5 years of age and younger) is common. The majority of severe episodes are triggered by viral colds. Unlike atopic asthma in adults and young…
Bronchiectasis and Chronic Suppurative Lung Disease
Abstract Bronchiectasis, chronic suppurative lung disease, and protracted bacterial bronchitis (PBB) are increasingly recognized conditions. Bronchiectasis is now again increasingly diagnosed, and its renewed interest has resulted in further in-depth…
