Abstract Interpretation of lung biopsy specimens is an integral part in the diagnosis of interstitial lung disease (ILD). The process of evaluating a surgical lung biopsy for disease involves answering…
Abstract The connective tissue diseases (CTDs) are inflammatory, immune-mediated disorders in which interstitial lung disease (ILD) is common and clinically important. ILD may be the first manifestation of a CTD…
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and ultimately fatal disease of the lung with an unknown etiology and few treatment options. Recognition of patients who fall into…
Abstract Cigarette smoke is recognized as the primary causative agent of certain interstitial lung diseases (ILDs), namely respiratory bronchiolitis–associated ILD, desquamative interstitial pneumonia, and pulmonary Langerhans cell histiocytosis. Cigarette smoking…
Abstract Interstitial lung diseases (ILDs) encompass a wide range of diffuse pulmonary disorders, characterized by a variable degree of inflammatory and fibrotic changes of the alveolar wall and eventually the…
Keywords Diffuse parenchymal lung disease, Interstitial lung disease, Lung disease, Lung transplantation, Parenchymal lung disease, Pulmonary Langerhans cell histiocytosis Key Points • For selected parenchymal lung disease (DPLD) patients…
Abstract In spite of many studies, the real nature, etiology, pathobiology, and therapy of acute exacerbation (AEx) of idiopathic pulmonary fibrosis (IPF) are not clear. It seemed that AEx-IPF may…
Abstract The care of patients with idiopathic pulmonary fibrosis requires multidisciplinary management integrating disease-specific therapy with treatment of comorbidities as well as symptom palliation. This review focuses on the role…
Abstract Idiopathic pulmonary fibrosis (IPF) is the most studied interstitial lung disease regarding symptom burden and perceived benefits and barriers to use of palliative care. Patients are without disease-reversing treatment…
Abstract In 2000, the American Thoracic Society and European Respiratory Society published the first consensus statement providing guidelines on the diagnosis and treatment of idiopathic pulmonary fibrosis (IPF). This statement…
