Management of Aneurysms in Takayasu’s Arteritis

Jul 10, 2016 by in CARDIAC SURGERY Comments Off on Management of Aneurysms in Takayasu’s Arteritis

Fig. 23.1 Juzenkai Zasshi, vol. 50, 1908, photograph courtesy of the Collections of the Department of Ophthalmology, Kanazawa University Epidemiology TA is an uncommon chronic inflammatory vasculitis, with an incidence…

read more

Platelets and Coronary Artery Disease

Jul 10, 2016 by in CARDIAC SURGERY Comments Off on Platelets and Coronary Artery Disease

Fig. 35.1 Platelets induce chemotactic, adhesive, and proteolytic properties of endothelial cells However, platelet IL-1β not only modifies endothelial release of chemotactic proteins, but it also has the potential to…

read more

Heart Valve Surgery and the Antiphospholipid Syndrome

Jul 10, 2016 by in CARDIAC SURGERY Comments Off on Heart Valve Surgery and the Antiphospholipid Syndrome

Author Year Ref. Brain Vasc Eye Spleen Heart Intestinal Kidney P. valve No TE Death FU Alvarez-Blanco A 1994 [25]        1    Schumacher M 1995 [26]            Sakaguchi G 1998 [27]            Myers…

read more

Neurohormonal Factors in Pediatric Heart Surgery

Jul 10, 2016 by in CARDIAC SURGERY Comments Off on Neurohormonal Factors in Pediatric Heart Surgery

Effects of sympathetic stimulation Cellular effects Heart Increased cardiomyocyte calcium entry Increased contractility (inotropy) Myocardial hypertrophy Increased heart rate Gene expression: Increased wall stress Increased expression of fetal genes Decreased…

read more

Mechanical Unloading and Heart Remodeling Features

Jul 10, 2016 by in CARDIAC SURGERY Comments Off on Mechanical Unloading and Heart Remodeling Features

Hypertrophy Contractile dysfunction Calcium cycling Cytoskeletal proteins (sarcomeric, non-sarcomeric, membrane) Beta-adrenergic signaling Metabolism and bioenergetics Myocyte death (apoptosis, autophagy, stress) Endothelium and microvasculature Sympathetic innervation Circulating neurohormones, cytokines Cardiac Hypertrophy…

read more
Get Clinical Tree app for offline access