Coronary heart disease Acute coronary syndromes Hypertension Often associated with left ventricular hypertrophy and preserved ejection fraction Cardiomyopathies Familial/genetic or non-familial/non-genetic (including acquired, e.g. myocarditis) Hypertrophic (HCM), dilated (DCM), restrictive…
Fig. 28.1 Thoratec HeartMate II Left Ventricular Assist Device (LVAD). Left; LVAD system complete with external controller connected to the LVAD via a percutaneous drive line with power input from…
Fig. 19.1 This figure demonstrates the subtle differences in ischemic mitral regurgitation (IMR) and functional mitral regurgitation (FMR) (Reprinted from Timek and Miller [7], © 2011, with permission from Elsevier)…
Structural heart disease Reentry Triggered activity Automaticity Infarct-related cardiomyopathy Coronary artery disease/Myocardial infarction ++++ + ++ Non-ischemic cardiomyopathy Dilated cardiomyopathy ++++ + ++ Hypertrophic cardiomyopathy ++++ + + Arrhythmogenic RV…
Fig. 21.1 Steps in T lymphocyte activation and proliferation. Panel a Multiple signals are required for T cell activation and proliferation in response to alloantigen recognition. Panel b Donor antigens…
Fig. 30.1 Stem and progenitor cells defined by proliferative and differentiation capacity. This figure depicts the reduction in proliferative potential and differentiation potential during cell maturation. It should be kept…
Fig. 22.1 Interplay of Donor and host immune responses in cardiac AMR B cells are critical players in the pathogenesis of the antibody mediated immune response. B-cell immunoglobulin protein receptors…
Fig. 35.1 Animal models of heart failure. (a) Sham (b) Pressure overloaded model after suprarenal ligation (c) Volume overloaded model after mitral regurgitation (d) Mixed load remodeling model after myocardial…
Fig. 29.1 The CardioWest Total Artificial Heart (TAH). The TAH consists of two pneumatically driven pulsatile pumps that replace the ventricle and four heart valves. The device is connected to…
Fig. 4.1 A comparison of typical pressure-volume loops for a single cardiac cycle of the left ventricle (a) and right ventricle (b). In the left ventricle, pressure continues to increase…
