Present Concepts in the Molecular Biology of Lung Cancer
Present Concepts in the Molecular Biology of Lung Cancer David H. Harpole Jr. Mark Onaitis Over the past decade, the study of cancer has increasingly focused upon molecular causes. This…
Pathology of Carcinoma of the Lung
Pathology of Carcinoma of the Lung Thomas W. Shields Derivation of Tumor Cell Types In the normal lung, stem cell activity, according to Otto and Wright,204 involves three cell types:…
The Sentinel Lymph Node in Non-Small-Cell Carcinoma of the Lung
The Sentinel Lymph Node in Non-Small-Cell Carcinoma of the Lung Michael J. Liptay The concept of a sentinel node associated with primary solid tumors was initially put forth by Cabanas…
Investigation and Management of Nodules Less than One Centimeter in Size
Investigation and Management of Nodules Less than One Centimeter in Size Ryosuke Tsuchiya Computed tomography (CT) has been used to evaluate patients suspected of having a solitary pulmonary nodule. Muhm…
Screening for Lung Cancer: Challenges for Thoracic Surgery
Screening for Lung Cancer: Challenges for Thoracic Surgery Brendon M. Stiles Nasser K. Altorki David F. Yankelevitz Lung cancer is a global health burden and is among the most common…
Lung Cancer: Epidemiology and Carcinogenesis
Lung Cancer: Epidemiology and Carcinogenesis Charles S. Dela Cruz Lynn T. Tanoue Richard A. Matthay Carcinoma of the lung is the leading cause of cancer death in the United States…
Editors’ Note on Revision of the Staging System for Lung Cancer
Editors’ Note on Revision of the Staging System for Lung Cancer Joseph LoCicero III MD Carolyn E. Reed MD Richard H. Feins MD Thomas W. Shields MD At the time…
Clinical Trial Design
Clinical Trial Design Mary W. Redman John J. Crowley For thoracic surgery as well as for any other discipline of medicine, the best path toward increased knowledge and better outcomes…
Lung Transplantation
Lung Transplantation Felix G. Fernandez G. Alexander Patterson Historical Review Early Phase During the early 1950s, Metras78 in France and Hardin and Kittle51 in the United States reported successful canine…
Evidence-Based Thoracic Surgery
Evidence-Based Thoracic Surgery Jemi Olak Paul J. Karanicolas “Evidence-based medicine” (EBM) represents a shift in medical paradigms. Traditional approaches to clinical decision making put a relatively high value on intuition,…
