Principles of Clinical Trials
Chapter 19 Principles of Clinical Trials Ruth McBride, April Slee Introduction A clinical trial is a medical study in humans. Typically, these studies are conducted to determine the efficacy and…
Disorders of Intracellular Transport and Intercellular Conduction
Chapter 8 Disorders of Intracellular Transport and Intercellular Conduction Andrew L. Wit, Heather S. Duffy Disorders of Intercellular Trafficking The cardiac action potential is formed by stringent coordination of ion…
Autonomic Nervous System and Cardiac Arrhythmias
Chapter 5 Autonomic Nervous System and Cardiac Arrhythmias David G. Benditt, Scott Sakaguchi, J. Gert van Dijk The autonomic nervous system (ANS) comprises the portion of the central nervous system…
Ion Channelopathies: Mechanisms and Genotype-Phenotype Correlations
Chapter 7 Ion Channelopathies Mechanisms and Genotype-Phenotype Correlations Charles Antzelevitch, Jonathan M. Cordeiro Recent years have witnessed an explosion of knowledge contributing to the understanding of ion channelopathies associated with…
Fundamentals of Regenerative Medicine and Its Applications to Electrophysiology
Chapter 9 Fundamentals of Regenerative Medicine and Its Applications to Electrophysiology David H. Lau, Michael R. Rosen The adult human heart has long been accepted as an end organ having…
Principles of Cellular Architecture and Physiology with Applications in Electrophysiology
Chapter 2 Principles of Cellular Architecture and Physiology with Applications in Electrophysiology Thomas J. Hund, Shane R. Cunha, Peter J. Mohler Specialized Excitable Cells Tightly Regulate Cardiac Depolarization The highly…
Electrophysiological Evaluation of Syncope
Chapter 29 Electrophysiological Evaluation of Syncope Hugh Calkins Introduction This chapter reviews the role of electrophysiology (EP) testing and tilt-table (TT) testing in the evaluation of patients with syncope. A…
Genomics and Principles of Clinical Genetics
Chapter 6 Genomics and Principles of Clinical Genetics David J. Tester, Michael J. Ackerman The molecular millennium has provided researchers with the essential tools to identify the underlying genetic substrates…
Principles of Electropharmacology
Chapter 11 Principles of Electropharmacology Penelope A. Boyden, David Eisner Long before actual medicines were available for arrhythmias, much had been written about the theoretical mechanisms of arrhythmias.1,2 Today, these…
