Author, year n Study design Quality of evidence Wilson et al. (2002) [5] 16 Comparative (appropriate statistical methodology not used) Very low Swisher et al. (2002) [6] 13 Comparative (nCR…
Author Patients Findings Recommendations Schwarz et al. (2007): SEER database 1973–2003 [4] 5,620 Higher total LN count (>30) and negative LN count (>15) associated with improved survival (p < 0.001); Relative increase…
Mark K. Ferguson (ed.)Difficult Decisions in Surgery: An Evidence-Based ApproachDifficult Decisions in Thoracic Surgery3rd ed. 2014An Evidence-Based Approach10.1007/978-1-4471-6404-3_26 © Springer-Verlag London 2014 26. Regional Extent of Lymphadenectomy for Esophageal Cancer Hirofumi Kawakubo1, Hiryoya Takeuchi1 and Yuko Kitagawa1 …
Study Patients Outcome TTE THE Relative risk for THE Quality of evidence Goldminc et al. (1993) [12] TTE, n = 35 Anastomotic leak 9 % 6 % 0.66 (p = NS) Level 1B THE,…
Authors, reference Year of publication Histology (no. of AC/SCC)/stage Study design Treatment Effect Hazard ratio (95 % CI) Quality of evidence Bedenne et al. [5] 2007 SCC(n = 239); AC(n = 29)/T3N0-1 RCT Neoadjuvant…
Fig. 22.1 An algorithm reflecting current standard approach for patients with Barrett’s associated neoplasia A Personal View of the Data My approach systematically begins with counseling patients on all options…
Study Histology Treatment No. of patients % pCR Treatment related mortality (%) Survival Quality of evidence Kelsen et al. [2] SCC 59.7 % CDDP + 5FU + S 213 2.5 6.4 23…
Mark K. Ferguson (ed.)Difficult Decisions in Surgery: An Evidence-Based ApproachDifficult Decisions in Thoracic Surgery3rd ed. 2014An Evidence-Based Approach10.1007/978-1-4471-6404-3_20 © Springer-Verlag London 2014 20. Extracorporeal Support for Lung Grafts Prior to Transplantation Axel Haverich1 and Christian Kuehn1…
Author (year) Study date range # studies/# patients Histology 5-year survival Prognostic factors Gonzales (2013) [11] 2000–2011 25/2,925 Colorectal carcinoma R0 27–68 % Disease free interval, number of pulmonary mets,…
Dysfunction Clinical example Devices available Concept Benefits Drawbacks Respiratory failure H1N1 infection vvECMO Oxygenation only CO2 only vv ECMO, NovaLung A membrane with inflow from systemic artery (femoral) with return…
