CMD in Myocardial Diseases
Fig. 5.1 Typical asymmetric LVH, which dramatically involves the interventricular septum, in a patients with HCM deceased due to sudden death. Adapted from Cecchi et al. [15] Many patients with HCM…
CMD in Obstructive CAD
Fig. 6.1 Left panel: total occlusion of the left anterior descending (LAD) coronary artery which is completely reperfused by collateral vessels from the right coronary artery (RCA) in a patient with…
Treatment of Primary CMD
Fig. 8.1 Effect of olmesartan and amlodipine on CFR in patients with arterial hypertension. Adapted from Naya et al. [10] The favorable effects of antihypertensive drugs on CMD, therefore, likely mainly…
Iatrogenic Coronary Microvascular Dysfunction
Fig. 7.1 Top panel. Left: pre-procedural angiogram of the right coronary artery showing a 60–70 % mid-vessel stenosis; middle: Intravascular ultrasound (IVUS) examination (4 slices taken at 1-mm distance in the middle…
Treatment of CMD in Obstructive CAD
Fig. 10.1 Therapeutic interventions potentially able to promote collateral vessel growth. Adapted from Chillian et al. [1] Gene therapy initially appeared as the most applicable and potentially valid form of therapy…
Prevention of Iatrogenic CMD
Fig. 11.1 The Kaplan-Meier curves show the main results of a randomized trial testing the use of a distal embolic protection device during PCI of saphenous vein aorto-coronary bypass grafts A…
Treatment of CMD in Myocardial Diseases
Fig. 9.1 Panel a. Myocardial efficiency at baseline and 6 months (follow-up) after alcohol septal ablation in patients with HCM. Panel b. Linear relationship between the changes (baseline vs. 6 months after alcool…
