Congestive Heart Failure as a Consequence of Valvular Heart Disease William J. McKenna Denis Pellerin Niall G. Mahon Barry H. Greenberg The management of patients with congestive heart failure (CHF)…
The Cardiomyopathic and Inflammatory Diseases Jeffrey David Hosenpud Bart L. Cox The concept of primary myocardial disease was first suggested in the late nineteenth century by Krehl, who described several…
Heart Failure Sedondary to Coronary Artery Disease Roger M. Millis Jr. Mourz Al-Mallah This chapter reviews current important basic and clinical aspects of heart failure that occur as a consequence…
Risk Factors for Heart Failure Javed Butler “If you wish to speak to me, you should first define your terms.” —Master Pangloss to Candide in Voltaire’s Candide Risk Factor Determination:…
The Kidney in Heart Failure JoAnn Lindenfeld Robert W. Schrier Sodium and water retention are hallmarks of heart failure (HF) and link the heart and kidney in this common medical…
The Peripheral Circulation in Heart Failure Anju Nohria Mark A. Creager The development and progression of myocardial failure are heralded by the activation of circulating neurohormonal systems that modulate both…
Cytokines as Mediators of Disease Progression in the Failing Heart Douglas L. Mann Since the original description of inflammatory cytokines in patients with heart failure in 1990 (1), there has…
Other Neurohormonal Systems Steven Goldsmith Bradley A. Bart Interference with the maladaptive consequences of imbalances in activity of the renin-angiotensin-aldosterone system (RAAS) and the adrenergic nervous system forms the bedrock…
Sympathetic Nervous System in Heart Failure G. Michael Felker Wilson S. Colucci Howard A. Rockman The sympathetic nervous system (SNS) plays a central role in cardiovascular physiology by releasing endogenous…
The Renin-Angiotensin System Barry H. Greenberg Our understanding of the important role of the reninangiotensin system (RAS) in maintaining circulatory homeostasis and in the pathogenesis of cardiovascular disease has evolved…
