Clinical outcomes following unrestricted use of the everolimus-eluting stent as compared with paclitaxel- and sirolimus-eluting stents

Nov 16, 2017 by in CARDIOLOGY Comments Off on Clinical outcomes following unrestricted use of the everolimus-eluting stent as compared with paclitaxel- and sirolimus-eluting stents

Background There is currently a paucity of data regarding clinical outcomes after everolimus-eluting stent (EES) implantation [compared to paclitaxel-eluting stents (PES) and sirolimus-eluting stents (SES)] in unselected patients with the…

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High on-treatment platelet reactivity is associated with periprocedural myocardial infarction

Nov 16, 2017 by in CARDIOLOGY Comments Off on High on-treatment platelet reactivity is associated with periprocedural myocardial infarction

Background Both high on-treatment platelet reactivity and periprocedural myocardial infarction (MI) are associated with adverse events following percutaneous coronary intervention (PCI). The optimal method of quantifying platelet reactivity remains controversial….

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Treatment of smaller coronary vessels with XIENCE V everolimus-eluting stents in real-world patients: 1-year clinical outcomes from the XIENCE V USA study

Nov 16, 2017 by in CARDIOLOGY Comments Off on Treatment of smaller coronary vessels with XIENCE V everolimus-eluting stents in real-world patients: 1-year clinical outcomes from the XIENCE V USA study

Background Patients with lesions located in small vessels are at increased risk of adverse outcomes after PCI. Improved safety and efficacy have been previously demonstrated with XIENCE V stents in…

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Genetic deficiency of cystathionine gamma-lyase exacerbates myocardial reperfusion injury and is rescued by exogenous hydrogen sulfide

Nov 16, 2017 by in CARDIOLOGY Comments Off on Genetic deficiency of cystathionine gamma-lyase exacerbates myocardial reperfusion injury and is rescued by exogenous hydrogen sulfide

Hydrogen sulfide (H 2 S) is a novel gaseous signaling molecule that up-regulates antioxidants, anti-apoptogens, and promotes cellular survival. In the heart, cystathionine gamma-lyase (CSE) is the primary enzyme for…

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Procedural and postoperative outcomes following balloon aortic valvuloplasty in severe aortic stenosis patients with left ventricular ejection fractions <20%

Nov 16, 2017 by in CARDIOLOGY Comments Off on Procedural and postoperative outcomes following balloon aortic valvuloplasty in severe aortic stenosis patients with left ventricular ejection fractions <20%

Background Severe aortic stenosis (AS) patients with left ventricular ejection fraction (LVEF) <20% are currently excluded from transcatheter aortic valve implant trials and are believed to be at higher risk…

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Percutaneous recanalization of central veins access for pacemaker/cardioverter–defibrillator implantation or upgrade

Nov 16, 2017 by in CARDIOLOGY Comments Off on Percutaneous recanalization of central veins access for pacemaker/cardioverter–defibrillator implantation or upgrade

Background Patients undergoing pacemaker and/or cardioverter–defibrillator (PM/ICD) implantation/upgrade might have difficult access due to sub/total central vein occlusions, usually related to prior venous manipulation. This study aimed to describe the…

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A North American population’s predictors of early clopidogrel discontinuation after drug-eluting stent implantation

Nov 16, 2017 by in CARDIOLOGY Comments Off on A North American population’s predictors of early clopidogrel discontinuation after drug-eluting stent implantation

Background The association between early discontinuation of clopidogrel after drug-eluting stent (DES) implantation and an increased risk of adverse cardiovascular events is well documented. However, little is known about the…

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