Angiotensin-converting enzyme therapy and the risk of contrast-induced nephropathy after coronary angiography and percutaneous coronary intervention

Nov 16, 2017 by in CARDIOLOGY Comments Off on Angiotensin-converting enzyme therapy and the risk of contrast-induced nephropathy after coronary angiography and percutaneous coronary intervention

Background The effects of angiotensin-converting enzyme inhibitors (ACEI) on the incidence of post-cardiac catheterization contrast-induced nephropathy (CIN) are not well understood. Some studies suggest that ACEI may contribute to CIN,…

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Relationship between platelet reactivity inhibition and major bleeding in patients undergoing percutaneous coronary intervention

Nov 16, 2017 by in CARDIOLOGY Comments Off on Relationship between platelet reactivity inhibition and major bleeding in patients undergoing percutaneous coronary intervention

Background Optimal platelet inhibition is critical to prevent ischemic events following percutaneous coronary intervention (PCI). However, recent studies have suggested that excessive inhibition may favor bleedings. We aimed to investigate…

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Optimizing the pharmacoinvasive approach to acute ST-segment elevation myocardial infarction: use of half-dose thrombolytic therapy in combination with glycoprotein IIb/IIIa receptor inhibitors compared with full-dose thrombolytic therapy in the setting of routine urgent post-thrombolytic percutaneous coronary intervention

Nov 16, 2017 by in CARDIOLOGY Comments Off on Optimizing the pharmacoinvasive approach to acute ST-segment elevation myocardial infarction: use of half-dose thrombolytic therapy in combination with glycoprotein IIb/IIIa receptor inhibitors compared with full-dose thrombolytic therapy in the setting of routine urgent post-thrombolytic percutaneous coronary intervention

Background Many studies have shown that a pharmacoinvasive strategy of urgent percutaneous coronary intervention following thrombolytic therapy in ST-segment elevation myocardial infarction (STEMI) patients is associated with better outcomes than…

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Adverse outcomes in patients prescribed a proton pump inhibitor following percutaneous coronary intervention with drug-eluting stents

Nov 16, 2017 by in CARDIOLOGY Comments Off on Adverse outcomes in patients prescribed a proton pump inhibitor following percutaneous coronary intervention with drug-eluting stents

Background Recent evidence shows that clopidogrel and proton pump inhibitors (PPI) are metabolized by the same pathway, and patients taking both drugs have higher levels of platelet reactivity and more…

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The impact of chronic obstructive pulmonary disease on hemodynamics and outcome in patients with acute myocardial infarction

Nov 16, 2017 by in CARDIOLOGY Comments Off on The impact of chronic obstructive pulmonary disease on hemodynamics and outcome in patients with acute myocardial infarction

Background Patients with chronic obstructive pulmonary disease (COPD) often present with pulmonary hypertension and right ventricular dysfunction. The impact of the reduction in cardiac reserve imposed by COPD on outcome…

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Single- versus multiple-vessel stenting for patients with ST-elevation myocardial infarction: results from a 30,886-patient meta-analysis

Nov 16, 2017 by in CARDIOLOGY Comments Off on Single- versus multiple-vessel stenting for patients with ST-elevation myocardial infarction: results from a 30,886-patient meta-analysis

Background There is uncertainty on the most appropriate management of patients with acute ST-elevation myocardial infarction (STEMI) and concomitant multivessel coronary artery disease. We thus performed a systematic review and…

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Predictors for choosing trans-femoral approach in a center where trans-radial approach is routinely used for coronary angiography

Nov 16, 2017 by in CARDIOLOGY Comments Off on Predictors for choosing trans-femoral approach in a center where trans-radial approach is routinely used for coronary angiography

Background In centers where trans-radial approach (TRA) is routinely used for coronary angiography (CA), little data is available on the predictors for choosing trans-femoral approach (TFA). Methods We performed a…

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Three-year outcomes following sirolimus- versus paclitaxel-eluting stent implantation in an unselected population with coronary artery disease: The REWARDS Registry

Nov 16, 2017 by in CARDIOLOGY Comments Off on Three-year outcomes following sirolimus- versus paclitaxel-eluting stent implantation in an unselected population with coronary artery disease: The REWARDS Registry

Background Safety concerns have necessitated the assessment of longer-term outcomes of patients treated with drug-eluting stents (DES). This study aimed to examine whether there is a difference in long-term outcomes…

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