Novel Combination Therapy to Target Heart and Kidney

Jul 10, 2016 by in CARDIOLOGY Comments Off on Novel Combination Therapy to Target Heart and Kidney

Compounds Adverse clinical cardiorenal outcomes Cardiac effects Vascular effects Renal effects Indoxyl sulfate Progression of CKD [26, 27] Increased collagen synthesis in NCF [34] Defective endothelial proliferation and wound repair…

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Renal Congestion in Heart Failure

Jul 10, 2016 by in CARDIOLOGY Comments Off on Renal Congestion in Heart Failure

Fig. 9.1 Mechanisms involved in renal congestion in heart failure How Does Renal Congestion Lead to Worsening of Renal Function? As suggested above venous congestion (including renal vein) is an…

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Is “Me, Me, Me” the New “We, We, We”?: Can We Afford (Not) to Take the Plunge into the Personalised, Stratified Medicine Era?

Jul 10, 2016 by in CARDIOLOGY Comments Off on Is “Me, Me, Me” the New “We, We, We”?: Can We Afford (Not) to Take the Plunge into the Personalised, Stratified Medicine Era?

Cancer type Cellular target Targeted agent Class of agent Colorectal [16–18] KRAS Cetuximab Monoclonal antibody against EGFR Breast [19, 20] HER2 Trastuzumab Monoclonal antibody HER2/Neu (EGFR2) Chronic myeloid leukaemia [21,…

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How to Use Inhibitors of the Renin-Angiotensin-Aldosterone System in Patients with CKD and Heart Failure

Jul 10, 2016 by in CARDIOLOGY Comments Off on How to Use Inhibitors of the Renin-Angiotensin-Aldosterone System in Patients with CKD and Heart Failure

© Springer International Publishing Switzerland 2015David Goldsmith, Adrian Covic and Jonas Spaak (eds.)Cardio-Renal Clinical Challenges10.1007/978-3-319-09162-4_15 15. How to Use Inhibitors of the Renin-Angiotensin-Aldosterone System in Patients with CKD and Heart Failure Dan Gaiţă1  , Svetlana Moşteoru1   and Liviu Segall2   (1)…

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Small Vessel Disease in CKD, Diabetes, Obesity and Hypertension

Jul 10, 2016 by in CARDIOLOGY Comments Off on Small Vessel Disease in CKD, Diabetes, Obesity and Hypertension

© Springer International Publishing Switzerland 2015David Goldsmith, Adrian Covic and Jonas Spaak (eds.)Cardio-Renal Clinical Challenges10.1007/978-3-319-09162-4_2 2. Small Vessel Disease in CKD, Diabetes, Obesity and Hypertension Reza Aghamohammadzadeh1  , Emma C. Wylie2   and Anthony M. Heagerty1   (1) Institute of Cardiovascular Sciences, The University…

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