DRUG Toxic dose range Cardiac toxicity % Doxorubicin Epirubicin >450 mg/m2 >900 mg/m2 Left venticular dysfunction 3–12% 0.9–3.3% Paclitaxel Docetaxel Conventional dose Left venticular dysfunction 5–15% 2.3–8% Cyclophosphamide >100–120 mg/kg Left venticular dysfunction…
Classification Systolic BP (mmHg) Diastolic BP (mmHg) Normal <120 <80 Prehypertension 120–139 80–89 Stage 1 140–159 90–99 Stage 2 >160 >100 Within oncology, the Common Terminology Criteria for Adverse Events…
© Springer International Publishing Switzerland 2017Gretchen G. Kimmick, Daniel J. Lenihan, Douglas B. Sawyer, Erica L. Mayer and Dawn L. Hershman (eds.)Cardio-Oncology10.1007/978-3-319-43096-6_7 7. Radiation Therapy and Cardiotoxicity Manisha Palta1 , Chang-Lung Lee2 , Syed Wamique Yusuf3 and David G. Kirsch2 (1) Department of Radiation Oncology, Duke…
