Autonomic Imaging: The Cardiorenal Axis
Type of syndrome Clinical features Type 1 Acute worsening of heart function leads to acute kidney injury and/or dysfunction Acute cardiorenal syndrome Type 2 Chronic abnormalities in heart function result…
Autonomic Imaging Cardiotoxicity with [123I]-MIBG: The Effects of Chemotherapy, Monoclonal Antibody Therapy, and Radiotherapy
Drug class/generic name (brand) Cardiac adverse events Relative frequency of adverse effecta Relative frequency of therapeutic use Anthracyclines/anthraquinones Doxorubicin (Adriamycin) CHF/LV dysfunction Common Very frequent Daunorubicin (Cerubidine) CHF/LV dysfunction Common…
Autonomic Imaging in Myocardial Ischemia
Fig. 14.1 [99mTc]-MIBI (upper) and 15 min (middle) and 3 h (lower) [123I]-MIBG SPECT images and polar maps from a patient with inferior myocardial infarction. Both 15 min and 3…
Imaging of the Autonomic Nervous System in Cardiac Amyloidosis
Fig. 16.1 An example of an abdominal subcutaneous fat aspirate exposing amyloid deposits, stained with Congo red. (a) Viewed in normal light: amyloid is stained red. Bar length is 200…
Role of the Autonomic Nervous System in Ventricular Arrhythmias During Acute Myocardial Ischemia and Infarction
Fig. 4.1 Example of increased left stellate ganglion nerve activity (SGNA) preceding ventricular fibrillation (VF) and sudden cardiac death (Zhou et al. 2008). (a) Increased low-amplitude burst discharge activity (LABDA)…
The Autonomic Nervous System of the Heart
Fig. 1.1 Scheme of the sympathetic and parasympathetic nervous system (see text for description) Fig. 1.2 Nerve connections between the spinal cord, spinal nerves, sympathetic nervous chain, and peripheral sympathetic…
Imaging Sympathetic Innervation of the Heart: Therapeutic Strategies SPECT/CT and PET/CT
Fig. 19.1 Delayed [123I]-MIBG images before (a, c) and after (b, d) CRT. Responder patient images with a HMR that improved from 1.66 to 2.01 (a, b). Non-responder patient images…
Autonomic Imaging in Heart Transplantation
Fig. 17.1 Polar maps of myocardial retention of C-11 metahydroxyephedrine ([11C]-mHED) in four cardiac transplant recipients at different times after surgery, illustrating time course and regional extent of sympathetic reinnervation…
Imaging the Cardiac Automatic Nervous System in Diabetes Mellitus
Fig. 15.1 A 61-year-old female with DM-2 and no cardiac complaints. Myocardial perfusion scintigraphy showed normal perfusion at rest and during exercise. Planar cardiac [123I]-MIBG scintigraphy at 15 min (i.e.,…
Imaging the Functional Brain-Heart Axis: Mental Stress and Cardiac Dysfunction
Fig. 22.1 Irreversible defect in the infero-postero-lateral wall on a [99mTc]-tetrofosmin myocardial perfusion SPECT scan (a), indicating myocardial infarction. Infarction in the inferior wall and basal infero-septal region on a…
