Summary Background The mechanism involved in the onset of aortic valve (AoV) disease remains unclear despite its poor prognosis and frequency. Recently, we reported that Krox20 ( EGR2 in humans)…
Summary Background Clinical studies have shown a beneficial effect of cardiac rehabilitation (CR) on mortality. Objective To study the effect of CR prescription at discharge on 5-year mortality in patients…
Summary Background Syncopes are frequent in the paediatric population. Most are benign, but rare cases are caused by cardiac life-threatening diseases. Syncope units developed in the adult population have demonstrated…
Summary Heart failure is a highly morbid syndrome generating enormous socio-economic costs. The failing heart is characterized by a state of deficient bioenergetics that is not currently addressed by classical…
Summary Background High-sensitivity cardiac troponin is the most specific and sensitive biomarker of myocardial injury. However, no study has investigated whether the early concentration of high-sensitivity cardiac troponin is increased…
Summary Background Trans-oesophageal echocardiography (TOE) is one of the major diagnostic tests in cardiovascular medicine, but the procedure is associated with some discomfort for the patient. Aim To determine the…
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy (1 per 200 with an inherited cardiomyopathy) . Half of all patients with HCM present with symptoms such as dyspnea on…
Summary The pleiotropic effects of statins, beyond their cholesterol-lowering properties, are much debated. In primary prevention, several observational cohort and case-control studies appear to show that statins reduce the incidence…
Carotid artery stenosis is the causative factor in 15–20% of patients with ischaemic stroke or transient ischaemic attack. In clinical trials, carotid endarterectomy (CEA) reduces the absolute risk of ischaemic…
