A 79-year-old man with a history of hypertension and dyslipidaemia was referred to our department with an anteroseptoapical ST-segment elevation myocardial infarction. Coronary angiography revealed a thin, thrombosed right coronary…
A 5-year-old Djiboutian boy was admitted to our hospital with shortness of breath after exertion. After every few steps, he had to stop and squat ( Fig. 1 A )….
Summary The proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates cholesterol metabolism mainly by targeting the low-density lipoprotein receptor (LDLR) for degradation in the liver. Gain-of-function mutations in PCSK9 are one…
Summary Many epidemiological studies have demonstrated that resting heart rate is a risk marker but also a risk factor in patients with coronary artery disease and heart failure. In hypertensive…
Summary Background Heart rate is a major determinant of myocardial oxygen demand; in ST-segment elevation myocardial infarction (STEMI), patients treated with primary percutaneous intervention (PPCI), heart rate at discharge correlates…
Summary Background Chronic heart failure (CHF) is a frequent severe disease. Disease-management programmes, which contain a therapeutic patient education component, will play a central role in improving delivery of care…
Summary Background Patient selection for transcatheter aortic valve implantation (TAVI) remains a major concern. Indeed, despite promising results, it is still unclear which patients are most and least likely to…
Summary Background Foetal echocardiography has been used to diagnose congenital heart disease. However, conventional echocardiography can only display two-dimensional (2D) structural images of the intricate three-dimensional (3D) foetal heart. Aim…
Antiplatelet agents remain a cornerstone of treatment for acute coronary syndrome. More than 15 years after the introduction of ticlopidine in coronary artery disease, the combination of aspirin with P2Y…
