A 7-week-old infant was referred to our department for refractory Kawasaki disease. Despite aggressive anti-inflammatory treatment, he had persistent biological and clinical inflammatory symptoms. Pulse corticosteroid therapy followed by infliximab…
An 80-year-old man was referred to our institution for recent dyspnoea on exertion associated with asthenia for a few months. Physical examination, blood tests, chest X-ray and spirometry were normal….
Summary Cardiovascular mortality has decreased over the past 25 years, largely because of acute coronary syndrome care and preventive actions. Nevertheless, the rate of coronary heart disease remains high, with…
Summary Rest is usually recommended in acute pericarditis and acute myocarditis. Given that myocarditis often leads to hospitalization, this task seems easy to carry out in hospital practice; however, it…
Summary Background Several studies have suggested that proton-pump inhibitors (PPIs), mostly omeprazole, interact with clopidogrel efficacy by inhibiting the formation of its active metabolite via CYP2C19 inhibition. Whether this occurs…
Summary Background The operative risk of cardiac surgery is ascertained preoperatively on the basis of scores validated in multinational studies. However, the value they add to a simple bedside clinical…
Summary Background Despite favorable results of randomized studies and several guidelines, screening for abdominal aortic aneurysm is poorly implemented in most countries. In order to implement an effective abdominal aortic…
Summary Background In patients with myotonic dystrophy type 1 (DM1), the mechanisms underlying sudden cardiac death, which occurs in up to 1/3 of patients, are unclear. Aims To study the…
Myocardial fibres of the left ventricle (LV) have a spiral orientation, the subendocardial and subepicardial fibres being longitudinally orientated and the midwall fibres being circumferentially orientated. As a result, during…
