A full-term baby presented at 2 weeks of life with severe congestive heart failure. On clinical examination a 2/6 holosystolic murmur was found, bounding femoral pulses and hepatomegaly. Echocardiography found…
A 68-year-old woman presenting with metastatic carcinoid tumours of the liver and pancreas was referred for CMR imaging because of LV location on somatostatin receptor scintigraphy imaging, a specific test…
A 78-year-old woman with a history of hypertension was admitted to the intensive care unit for cardiogenic shock. Results of physical examination showed low systolic blood pressure (85 mmHg), tachycardia,…
A 16-year-old girl was admitted for breathlessness. Her only medical history was asthma treated with a bronchodilator and steroids. Examination revealed hepatomegaly, lower limb oedema and a soft systolic murmur…
Summary Despite the progress achieved in conventional treatment modalities, heart failure remains a major cause of mortality and morbidity. The identification of novel signaling pathways has provided a solid scientific…
Summary Despite considerable advances in pharmacological, surgical and technology-based cardiovascular therapy, left ventricular dysfunction and heart failure are increasingly prevalent health problems. Recent studies suggest that angiogenic gene therapy can…
Summary Background Compliance with guidelines for the management of ST-segment elevation myocardial infarction (STEMI) may be difficult in hard-to-access areas. Aims To analyse the characteristics, management and outcome of STEMIs…
Summary Telomeres are structures composed of deoxyribonucleic acid repeats that protect the end of chromosomes, but shorten with each cell division. They have been the subject of many studies, particularly…
Summary Background Tako-Tsubo cardiomyopathy is a clinical entity mimicking acute coronary syndrome. Assessment of left ventricular function may be difficult using conventional echocardiography. Aims To characterize left ventricular systolic function…
Summary Background The CONNECT study compared clinician adherence to guideline-recommended secondary prevention therapies prescribed at discharge for patients hospitalized for acute coronary syndrome (ACS) in those managed initially with percutaneous…
