Introduction Macao Follow up Study 2011 was a phone follow up to the participants who showed up in the Macao Health Survey 2006 (MHS2006). The response rate of the follow…
Objective Neutrophil to lymphocyte ratio is a novel parameter for cardiovascular research area. The higher values of neutrophil to lymphocyte ratio have been found to be associated with worse clinical…
Objective Heart Failure comprises huge medical attention causing distinctive mortality and morbidity especially in westernized societies with a great impact on health care envisioning. The present study aimed to evaluate…
Objective Herein, we studied the functional interaction between 5-HT2B receptor blocker (SB-204741) and GSK-3β inhibitor (SB-216763) in myocardial-ischemia reperfusion injury in rats. Methods To evaluate this hypothesis, either SB-204741 or…
Objective Oxidative stress has a prominent role in the cathecolamine induced cardiac damage. The aim of this study is to investigate whether resveratrol (RVT) ameliorates isoproterenol (ISO) induced myocardial damage…
Objectives The present study was designed to investigate the cardioprotective effect of sodium nitrite (NaNO2) and sodium nitrate (NaNO3) against myocardial ischemia-reperfusion (I/R) injury in a pig regional ischemia model….
Background Intermedin/Adrenomedullin 2 (IMD/AM2) is a novel peptide related to the calcitonin gene-related peptide family. It is a vascular regulatory factor of homeostasis and a vital endogenous protective factor against…
Background N-acetylcysteine, beta-glucan, and coenzyme Q10 have been shown to have antioxidant and anti-inflammatory effects on reperfusion injury. The aim of our study was to determine and evaluate the effects…
Introduction Pulmonary artery hypertension is devastating disease that has very serious outcomes. Dysregulated angiogenesis is one of the main responsible courses in pathophysiology of disease. Our experimental research intends to…
Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Many factors and substances may stimulate angiogenesis and exhibit proliferative effect. In this study, we aimed to investigate the…
