Objectives Factor XIII is a important key regulator of fibrinolysis and haemostasis. Factor XIII Valine34Leucine (Val34Leu) gene polymorphism has been associated with accelerated fibrin stabilization and increasing resistance to fibrinolysis….
Objectives Red cell distribution width (RDW) as an indicator of the variability in the circulating erythrocyte sizes was linked to chronic inflammatory state. The association of rheumatic heart valve stenosis…
Objective The purpose of this study was to reveal independent predictors of unfavorable course of active native valve infective endocarditis (ANVIE) and to determine impact of the surgery and its…
Subject The measurement of malcoaptation Surface Area assessed by trans-esophageal echocardiography has been introduced to differentiate severity of Aortic regurgitation(AR), but its value has not been accurately determined. The present…
Objective The role of systemic and chronic inflammatory processes in the pathophysiology of rheumatic heart valve disease is well-known. Neutrophil to lymphocyte ratio (NLR) was shown to be an indicator…
Objective Mitral valve prolapse (MVP) affects 2-4% of the general population and remains one of the most frequent indications for valvular surgery. Previous familial and pathophysiological studies suggest a complex…
Objectives Inflammation and oxidative stress play an important role in the pathogenesis of heart valve diseases (especially rheumatic valves). It is also known that matrix metalloproteinase is associated with myxomatous…
Background Coronary artery ectasia (CAE) has been established as a localized or diffuse non-obstructive lesion of the epicardial coronary arteries. Atherosclerosis plays an important role the etiopathogenesis of CAE. Inflammation…
Pathophysiological processes that initiate calcific aortic stenosis are still undefined and there are no currently available treatments that effect disease progression. The aim of this study was to evaluate pathologically,…
Objective Previous studies showed that both inflammation and platelets have had a role in slow coronary flow (SCF) development. Platelet-to-lymphocyte ratio (PLR) as an emerging inflammatory indicator was significantly associated…
