Cerebral embolic protection devices for transcatheter aortic valve replacement: A meta-analysis and trial sequential analysis

Jun 27, 2026 by in CARDIOLOGY Comments Off on Cerebral embolic protection devices for transcatheter aortic valve replacement: A meta-analysis and trial sequential analysis
Highlights • Routine use of current-generation CEPD was not associated with any difference in the incidence of any stroke, disabling stroke or all-cause mortality. • Trial sequential analysis indicates that,…
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Serial assessment of NT-proBNP and high-sensitivity cardiac troponin with glucagon-like peptide-1 receptor agonist therapy in type 2 diabetes: Insights from EXSCEL

Jun 27, 2026 by in CARDIOLOGY Comments Off on Serial assessment of NT-proBNP and high-sensitivity cardiac troponin with glucagon-like peptide-1 receptor agonist therapy in type 2 diabetes: Insights from EXSCEL
ABSTRACT Background In the EXSCEL trial, exenatide did not reduce major adverse cardiovascular events (MACE), but heterogeneity of benefit and the role of cardiac biomarkers remain uncertain. We evaluated the…
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Association between hospital ownership type and ST-segment elevation myocardial infarction outcomes: Insights from the National Readmission Database, 2016-2022

Jun 27, 2026 by in CARDIOLOGY Comments Off on Association between hospital ownership type and ST-segment elevation myocardial infarction outcomes: Insights from the National Readmission Database, 2016-2022
Highlights • Patients with STEMI at for-profit and public hospitals had greater socioeconomic needs than those at nonprofit hospitals. • For-profit hospitals had worse in-hospital mortality and 90-day readmission outcomes…
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Short-term outcomes of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction: A randomized pilot study

Jun 27, 2026 by in CARDIOLOGY Comments Off on Short-term outcomes of ticagrelor monotherapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction: A randomized pilot study
ABSTRACT Background Ticagrelor monotherapy after a short period of dual antiplatelet therapy (DAPT) has shown to be safe and effective after percutaneous coronary intervention (PCI), including primary PCI in ST-elevation…
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BAlloon expandable vs. SElf expanding transcatheter vaLve for degenerated bioprosthesIs (BASELINE trial): A protocol update

Jun 27, 2026 by in CARDIOLOGY Comments Off on BAlloon expandable vs. SElf expanding transcatheter vaLve for degenerated bioprosthesIs (BASELINE trial): A protocol update
The objective of the BAlloon Expandable vs. Self-Expanding Transcatheter VaLve for Degenerated Bioprosthesis (BASELINE) trial is to compare the balloon-expandable SAPIEN/MYVAL transcatheter heart valve (THV) series with the self-expanding EVOLUT…
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PIONEER IV trial: Update in study protocol

Jun 27, 2026 by in CARDIOLOGY Comments Off on PIONEER IV trial: Update in study protocol
The PIONEER IV trial (NCT04923191) is a prospective, all-comers, multi-centre trial, planned to randomize 2,540 patients in a 1:1 ratio to percutaneous coronary intervention (PCI) guided by angiography-derived physiology or…
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Secondary prevention strategies for patients with lower extremity peripheral artery disease after successful peripheral vascular intervention

Jun 27, 2026 by in CARDIOLOGY Comments Off on Secondary prevention strategies for patients with lower extremity peripheral artery disease after successful peripheral vascular intervention
Highlights • Lower extremity peripheral artery disease carries a high risk of subsequent morbidity and mortality, requiring aggressive secondary prevention therapies. • Secondary prevention therapies are particularly underutilized in the…
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Time-alignment considerations in evaluating AI-ECG–guided pulmonary valve replacement timing in repaired tetralogy of Fallot

Jun 27, 2026 by in CARDIOLOGY Comments Off on Time-alignment considerations in evaluating AI-ECG–guided pulmonary valve replacement timing in repaired tetralogy of Fallot
We read with great interest the report by Mayourian et al on the use of an artificial intelligence–enabled electrocardiogram (AI-ECG) to inform pulmonary valve replacement (PVR) timing in repaired tetralogy…
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Response to the letter: Time alignment considerations in evaluating AI-ECG guidance of pulmonary valve replacement timing in repaired tetralogy of Fallot

Jun 27, 2026 by in CARDIOLOGY Comments Off on Response to the letter: Time alignment considerations in evaluating AI-ECG guidance of pulmonary valve replacement timing in repaired tetralogy of Fallot
We thank Dr. Zablah and colleagues for their thoughtful comments on our study, which examines the use of artificial intelligence-enabled electrocardiogram (AI-ECG) to inform the timing of pulmonary valve replacement…
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