Beta-blocker side-effects in clinical practice: A nationwide approach

Jun 27, 2026 by in CARDIOLOGY Comments Off on Beta-blocker side-effects in clinical practice: A nationwide approach
Highlights • In a nationwide cohort of patients treated with beta-blockers for hypertension, we uncovered clinically relevant increased risks of depression, anxiety/insomnia, gastrointestinal side-effects, and dizziness/fainting compared with calcium-channel blockers….
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Artificial intelligence-enabled electrocardiogram guidance for pulmonary valve replacement timing in repaired tetralogy of Fallot

Jun 27, 2026 by in CARDIOLOGY Comments Off on Artificial intelligence-enabled electrocardiogram guidance for pulmonary valve replacement timing in repaired tetralogy of Fallot
Highlights • Pre-PVR AI-ECG was predictive of post-PVR survival in patients with rTOF. • AI-ECG complements imaging biomarkers for PVR risk stratification. • AI-ECG may help physicians to safely defer…
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Relationship between left atrial stiffness, pulmonary congestion, and impaired aerobic capacity in adults with repaired coarctation of aorta

Jun 27, 2026 by in CARDIOLOGY Comments Off on Relationship between left atrial stiffness, pulmonary congestion, and impaired aerobic capacity in adults with repaired coarctation of aorta
ABSTRACT Background Left atrial (LA) stiffness is linked to pulmonary congestion and exercise intolerance in patients with acquired form of heart failure but has not been studied in adults with…
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Association between conversion from an initial shockable rhythm to pulseless electrical activity before extracorporeal cardiopulmonary resuscitation and outcome: A secondary analysis of the SAVE-J II study

Jun 27, 2026 by in CARDIOLOGY Comments Off on Association between conversion from an initial shockable rhythm to pulseless electrical activity before extracorporeal cardiopulmonary resuscitation and outcome: A secondary analysis of the SAVE-J II study
Highlights • The rate of patients with favorable neurological outcomes was lower in patients who converted to PEA than in those with a sustained shockable rhythm (12.9 % vs 26.4…
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Response to letter by Hu regarding article, “Statistical Methodological Limitations and Improvement Suggestions in the Study of Vitamin D Deficiency and Cardiovascular Mortality After Heart Transplantation.”

Jun 27, 2026 by in CARDIOLOGY Comments Off on Response to letter by Hu regarding article, “Statistical Methodological Limitations and Improvement Suggestions in the Study of Vitamin D Deficiency and Cardiovascular Mortality After Heart Transplantation.”
We are writing in response to Hu and Wang’s letter, titled “Statistical Methodological Limitations and Improvement Suggestions in the Study of Vitamin D Deficiency and Cardiovascular Mortality After Heart Transplantation,”…
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Statistical methodological limitations and improvement suggestions in the study of vitamin D deficiency and cardiovascular mortality after heart transplantation

Jun 27, 2026 by in CARDIOLOGY Comments Off on Statistical methodological limitations and improvement suggestions in the study of vitamin D deficiency and cardiovascular mortality after heart transplantation
Highlights • Low EPV (4.9) risks unstable Cox model hazard ratios with 14 covariates. • CAV mediation (26.5%) lacks robustness from limited event numbers. • Penalized regression and sensitivity analyses…
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Medicare coverage gap status, adherence to oral anticoagulation, and stroke rates in patients with atrial fibrillation

Jun 27, 2026 by in CARDIOLOGY Comments Off on Medicare coverage gap status, adherence to oral anticoagulation, and stroke rates in patients with atrial fibrillation
Highlights • Medicare Part D included a coverage gap during which beneficiaries were responsible for substantially higher portions of medication costs, although the impact of this on oral anticoagulant prescription…
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Response to letter by Naeem regarding article, “Loop and thiazide diuretics and outcomes in heart failure with preserved ejection fraction”

Jun 27, 2026 by in CARDIOLOGY Comments Off on Response to letter by Naeem regarding article, “Loop and thiazide diuretics and outcomes in heart failure with preserved ejection fraction”
We thank Drs Qadir and Naeem for their insightful comments. We studied 1765 patients in the Americas cohort of TOPCAT, a randomized trial of spironolactone vs. placebo in patients with…
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