physiology Reza Anvari MD
CO2 in arterial blood crosses the blood brain barrier in CSF, CO2 combines with H2O produces H+ + HCO3–. • H+ acts in central chemoreceptors causing hyperventilation via vagus nerve…
CO2 in arterial blood crosses the blood brain barrier in CSF, CO2 combines with H2O produces H+ + HCO3–. • H+ acts in central chemoreceptors causing hyperventilation via vagus nerve…
Example of common I:E ratio setting:APRV 4:1 vs. AC 1:2 • It will increase mean airway pressure (Pmean) without increasing peak pressures. • It allows for superimposed spontaneous ventilation by the patient….
oxygen saturation • Gurgling noise with every breath • Low exhaled tidal volume alarm on ventilator • plateau pressures • peak pressures • pressure or PEEP • PCO2/Respiratory acidosis • Patient discomfort Problems…
compliance (“stiff lung”) plateau pressure; compliance plateau pressure. High plateau pressure increases the risk of barotrauma. Low plateau pressure can result in atelectasis and hypoventilation. Plateau pressure should not exceed…
Acute events overnight • Check vital signs Pulse rate Respiratory rate O2 saturation Blood pressure • Check fluid balance • Examine chest for Air entry Breath sounds Crackles Wheezing • Check endotracheal tube for…
Tachycardia, tachypnea Change in BP Dyspnea Noisy or shallow ventilation Rhonchi Obvious visible secretions Excessive coughing during inspiratory cycle of ventilator High-pressure alarm on vent Low SaO2 • Instillation of saline/saline…
65) have an abnormal swallow • after orotracheal intubation for more than 48 hours Diagnosis • Barium swallow with video fluoroscopy • Esophageal manometry • Endoscopy Treatment • Diet alteration, speech therapy • Temporary gastrostomy Tracheal…
FiO2 by 0.05-.10 increments PEEP by 2–3 cm H2O I:E ratio by changing the inspiratory time (Ti) Suctioning of secretions Use bronchodilators Use diuretics for pulmonary edema High PaO2 (O2…
Plateau >30 cmH2O Peak pressure >40 cmH2O VT > 12–15 ml/kg PEEP >10–15 cmH2O Ventilator-associated pneumonia • Refer to chapter 26 Oxygen toxicity • It is not clear what concentration…
Functional residual capacity Improves gas exchange and oxygenation Redistributes fluid in alveoli FiO2 requirement Helps prevent alveolar collapse Improves lung compliance Minimizes ventilator-induced lung injury Negative Effects Can worsen gas…