Fig. 13.1 Artist illustration of the club-shaped surface projections (peplomers) that give coronaviruses their unique coronal fringe by negative-staining electron microscopy (Illustration by Adrian Galvin, New York, NY) Fig. 13.2…

Virus family Genus Virus Disease Vector Geographicdistribution Case fatalityrate (%) Flaviviridae Flavivirus Yellow fever Yellow fever Mosquito Tropics, Africa, and South America 20 Dengue Dengue hemorrhagic fever Mosquito Throughoutthe tropics…

Fig. 21.1 EBV pneumonitis shows dense pulmonary perivascular and interstitial infiltrates 21.8 Lymphomatoid Granulomatosis Lymphomatoid granulomatosis was first described by Liebow and colleagues in 1972 as an angiocentric and angiodestructive…

Histopathology (1) Cytomegaly (2) Eosinophilic intranuclear Cowdry type B inclusions resembling an “owl’s eye” (3) Amphophilic intracytoplasmic inclusions Differential diagnosis Herpes simplex Varicella zoster Adenovirus Measles Reactive pneumocytes Radiographic findings…

Fig. 10.1 Lung biopsy with parainfluenza infection. (a) Acute and organizing pneumonia with bronchiolitis and multiple multinucleated giant cells consistent with infection by parainfluenza virus. (b, c) Multinucleated giant cell…

Fig. 14.1 Nipah virus. (a) Pulmonary vessels showing mild vasculitis and a multinucleated endothelial syncytium. (b) Interstitial pneumonitis. Note small vessel lined by a multinucleated endothelial cell. (c) Interstitial pneumonitis…

Fig. 16.1 Parvovirus infections in the lung are similar to those shown in other organs. This illustration shows the bone marrow of an immunocompromised patient. Note eosinophilic inclusions within early…

Fig. 8.1 Ultrastructure of the measles virus showing a spherical, enveloped virion with a non-segmented negative-stranded RNA genome (With permission from Lancet [Reproduced with permission of Exp. Rev. Mol. Med…