GENERAL

Advances in Coronary Revascularization

Mar 21, 2019 by in GENERAL Comments Off on Advances in Coronary Revascularization

Overview The field of coronary revascularization was revolutionized more than 50 years ago, when the first successful coronary artery bypass surgery was performed, followed shortly thereafter by the first percutaneous…

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Pharmacologic Options for Treatment of Ischemic Disease

Mar 21, 2019 by in GENERAL Comments Off on Pharmacologic Options for Treatment of Ischemic Disease

Organic Nitrates Overview Nitroglycerin (glyceryl trinitrate [GTN]) was first synthesized in 1847 by Ascanio Sobrero, who described a “violent headache” upon self-administration of a “minute quantity” of the drug. A…

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Global Cardiovascular Therapy

Mar 21, 2019 by in GENERAL Comments Off on Global Cardiovascular Therapy

Introduction to Global Challenges in Cardiovascular Disease Therapy Cardiovascular disease (CVD) has become the single greatest cause of death worldwide. In 2004, CVD caused an estimated 17 million deaths and…

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Systems of Health Care

Mar 21, 2019 by in GENERAL Comments Off on Systems of Health Care

A system is an interconnected set of elements organized to achieve a function or purpose. A system of care is an interconnected care delivery system, usually in a geographically contiguous…

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Pharmacogenetics

Mar 21, 2019 by in GENERAL Comments Off on Pharmacogenetics

Interindividual variability of drug response has been well documented. In addition to drug-drug and drug-environment interactions, genetic factors have emerged as contributors to variability in response to several cardiovascular medications….

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New Drug Development

Mar 21, 2019 by in GENERAL Comments Off on New Drug Development

Cardiovascular medicine has been in the vanguard of new therapeutic development since 1955, when President Dwight Eisenhower’s myocardial infarction (MI) in office captured worldwide attention. Many forces contribute to this…

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