Is Prasugrel a Better Antiplatelet Agent for Patients With Active Cancer and Coronary Artery Disease?

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Is Prasugrel a Better Antiplatelet Agent for Patients With Active Cancer and Coronary Artery Disease?

Dual antiplatelet treatment (DAPT) has emerged as the gold standard of treatment for patients with coronary artery disease (CAD). Combining two antiplatelet drugs makes sense. Aspirin inhibits the enzyme cyclooxygenase-1…

read more

A Win for a Win—The PROTECT Trials Through the Lens of Win Ratios

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on A Win for a Win—The PROTECT Trials Through the Lens of Win Ratios

In patients with severely depressed left ventricular (LV) function, percutaneous coronary intervention (PCI) may result in hemodynamic instability, leading to suboptimal revascularization and increased complications. Although there is a clear…

read more

Refining the Criteria for Left Ventricular Myocardial Dyssynchrony in Heart Failure

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Refining the Criteria for Left Ventricular Myocardial Dyssynchrony in Heart Failure

The success of cardiac resynchronization therapy in selected patients with heart failure and reduced left ventricular (LV) ejection fraction not adequately treated with medications has made it more important to…

read more

Blood Pressure–Adaptive Atrial Pacing Narrows Pulse Pressure in Hypertensive HFpEF

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Blood Pressure–Adaptive Atrial Pacing Narrows Pulse Pressure in Hypertensive HFpEF

Patients with heart failure with preserved ejection fraction (HFpEF) frequently exhibit widened pulse pressure (PP) and increased arterial stiffness, associated with impaired ventricular–arterial interaction and reduced functional capacity. Elevated PP…

read more

National Trends in Cardiovascular Disease Medication Dispensing Patterns During the COVID-19 Pandemic: Insights From the Department of Veterans Affairs

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on National Trends in Cardiovascular Disease Medication Dispensing Patterns During the COVID-19 Pandemic: Insights From the Department of Veterans Affairs

The COVID-19 pandemic disrupted routine healthcare delivery. Understanding how dispensing patterns of cardiovascular disease (CVD) medications changed during this period is essential to evaluating the continuity of chronic disease management….

read more

Impact of Prosthesis–Patient Mismatch After Surgical Mitral Valve Replacement: Systematic Review and Meta‐Analysis

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Impact of Prosthesis–Patient Mismatch After Surgical Mitral Valve Replacement: Systematic Review and Meta‐Analysis

The long-term clinical impact of mitral prosthesis–patient mismatch (PPM) after mitral valve replacement (MVR) remains incompletely defined. We aimed to systematically assess the prevalence of mitral PPM and its association…

read more

A Stepwise Multimodality Imaging Approach to Out-of-Hospital Cardiac Arrest in Cystic Fibrosis

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on A Stepwise Multimodality Imaging Approach to Out-of-Hospital Cardiac Arrest in Cystic Fibrosis

Out-of-hospital cardiac arrest (OHCA) without ST-segment elevation represents a challenging diagnostic scenario, particularly in young patients with low pretest probability of atherosclerotic disease. We report the case of a 25-year-old…

read more

Cardiovascular Complications During Delivery Hospitalizations in Patients With Infective Endocarditis

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Cardiovascular Complications During Delivery Hospitalizations in Patients With Infective Endocarditis

Highlights • Infective endocarditis during pregnancy is rare but carries high maternal and fetal morbidity and mortality. • Our study quantifies the contemporary burden of infective endocarditis in pregnancy and…

read more

Masquerading as the Great Masquerader: Pulmonary Artery Intimal Sarcoma Presenting as Pulmonary Embolism and Multiple Cavitary Lesions

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Masquerading as the Great Masquerader: Pulmonary Artery Intimal Sarcoma Presenting as Pulmonary Embolism and Multiple Cavitary Lesions

Pulmonary artery intimal sarcomas are rare and very aggressive tumors, with variable presentation, and are often misdiagnosed as acute pulmonary embolisms or chronic thromboembolic pulmonary hypertension. We report a case…

read more

Clinical Significance of Extreme Left Atrial Enlargement in Atrial Functional Mitral Regurgitation

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Clinical Significance of Extreme Left Atrial Enlargement in Atrial Functional Mitral Regurgitation

Highlights • The majority of patients with ≥ moderate atrial functional mitral regurgitation (AFMR) had a left atrium volume index (LAVI) 50 to 99 ml/m 2. • Excessive left atrium…

read more