CARDIOLOGY

Coronary CTO PCI is Associated With Higher In-Hospital Mortality and Complications Despite Adjusting for Baseline and High-Risk Characteristics

Aug 8, 2026 by in CARDIOLOGY Comments Off on Coronary CTO PCI is Associated With Higher In-Hospital Mortality and Complications Despite Adjusting for Baseline and High-Risk Characteristics
Percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) has shown a higher procedural risk. The goal of this study was to compare complications and mortality of patients undergoing CTO-PCI…
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Sacubitril/Valsartan and Prevention of Chemotherapy-Induced Cardiac Dysfunction: Meta-analysis of Randomized Trials

Aug 8, 2026 by in CARDIOLOGY Comments Off on Sacubitril/Valsartan and Prevention of Chemotherapy-Induced Cardiac Dysfunction: Meta-analysis of Randomized Trials
Chemotherapy-related cardiac dysfunction (CTRCD) is a major limitation of cardiotoxic cancer therapies. Although global longitudinal strain (GLS) allows early detection of myocardial injury, preventive strategies remain scarce. Angiotensin receptor–neprilysin inhibitors…
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Leaflet Modification for Bicuspid Aortic Valve Tricuspidalization Enabling Implantation of Larger Transcatheter Heart Valves

Aug 8, 2026 by in CARDIOLOGY Comments Off on Leaflet Modification for Bicuspid Aortic Valve Tricuspidalization Enabling Implantation of Larger Transcatheter Heart Valves
Severe raphe calcification in bicuspid aortic valve (BAV) remains a major challenge for transcatheter aortic valve replacement (TAVR), often leading to asymmetric valve expansion, residual gradients, and suboptimal durability. We…
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Efficacy and Safety of Olezarsen for the Management of Dyslipidemia: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials

Aug 8, 2026 by in CARDIOLOGY Comments Off on Efficacy and Safety of Olezarsen for the Management of Dyslipidemia: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials
This updated systematic review and meta-analysis evaluated the efficacy and safety of olezarsen in patients with dyslipidemia. PubMed, Embase, Cochrane CENTRAL, and Scopus were searched through September 2025 for randomized…
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Global Longitudinal Strain and Left Ventricular Mechanical Dispersion in Patients With Preserved Ejection Fraction and Sudden Cardiac Arrest

Aug 8, 2026 by in CARDIOLOGY Comments Off on Global Longitudinal Strain and Left Ventricular Mechanical Dispersion in Patients With Preserved Ejection Fraction and Sudden Cardiac Arrest
Specific tools are lacking for sudden cardiac arrest (SCA) risk assessment in patients with preserved left ventricular ejection fraction (LVEF) and nonhypertrophic ventricles. We hypothesized that echocardiographic global longitudinal strain…
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