Outcomes and Sex Differences in Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy–Insights from a Japanese Nationwide Registry

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Outcomes and Sex Differences in Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy–Insights from a Japanese Nationwide Registry

Recent advances in pre–procedural imaging have improved risk assessment and procedural planning for alcohol septal ablation (ASA) in patients with symptomatic obstructive hypertrophic cardiomyopathy (HOCM). However, limited data exist regarding…

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Hidden Conduction, Overt Risk: A Case of Wolff–Parkinson–White Syndrome Unmasked

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Hidden Conduction, Overt Risk: A Case of Wolff–Parkinson–White Syndrome Unmasked

Wolff–Parkinson–White syndrome, though previously diagnosed and without prior arrhythmic events, may remain clinically quiescent until atrial fibrillation with rapid antegrade conduction over an accessory pathway precipitates a potentially life threatening…

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Incidence, Predictors, and Outcomes of Stroke Following Transcatheter Aortic Valve Implantation: A Multicenter Australian Experience

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Incidence, Predictors, and Outcomes of Stroke Following Transcatheter Aortic Valve Implantation: A Multicenter Australian Experience

Highlights • Stroke remains uncommon following TAVI, but its incidence is not decreasing over time. • Previous radiotherapy is a novel predictor of post-TAVI stroke. • Self-expanding valves predicted stroke,…

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Stage-Dependent Diastolic Recovery and Reverse Remodeling After Atrial Fibrillation Ablation Across the Spectrum of Left Ventricular Diastolic Dysfunction

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Stage-Dependent Diastolic Recovery and Reverse Remodeling After Atrial Fibrillation Ablation Across the Spectrum of Left Ventricular Diastolic Dysfunction

Atrial fibrillation (AF) coexists with left ventricular diastolic dysfunction (LVDD), but the impact of catheter ablation across LVDD stages is unclear. The study aimed to quantify AF ablation effects on…

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Diffuse Extra-Thoracic Vascular Disease in Nonsyndromic Thoracic Aortic Aneurysm and Dissection

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Diffuse Extra-Thoracic Vascular Disease in Nonsyndromic Thoracic Aortic Aneurysm and Dissection

Patients with nonsyndromic thoracic aortic aneurysm and dissection (nsTAAD) may have systemic arterial involvement, but the distribution and clinical correlates of extrathoracic disease remain poorly defined. We conducted a retrospective…

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Secondary Access in Transfemoral TAVI: Strengths, Gaps, and What the RADIAL-TAVI Trial Still Needs to Address

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Secondary Access in Transfemoral TAVI: Strengths, Gaps, and What the RADIAL-TAVI Trial Still Needs to Address

The RADIAL-TAVI trial rationale and design paper by von Ehr et al. in The American Journal of Cardiology was fascinating. The study answers an important clinical question: whether using the…

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Oversizing Transcatheter Aortic Valves: Are We Getting It Right?

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Oversizing Transcatheter Aortic Valves: Are We Getting It Right?

Optimal valve sizing is critical in transcatheter aortic valve replacement (TAVR) to minimize complications and provide the best clinical and hemodynamic results. The objective of this study was to evaluate…

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Efficacy of Sodium–Glucose Cotransporter 2 Inhibitors in Heart Failure With Supra-Normal Ejection Fraction: A Target Trial Emulation Study

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Efficacy of Sodium–Glucose Cotransporter 2 Inhibitors in Heart Failure With Supra-Normal Ejection Fraction: A Target Trial Emulation Study

Highlights • Target trial emulation evaluated SGLT2 inhibitors in HFsnEF. • SGLT2i reduced cardiovascular death or heart failure hospitalization. • Findings support SGLT2i as a potential therapy for HFsnEF. The…

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Valvular Heart Disease During Pregnancy: Outcomes from a Large Integrated Healthcare System

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Valvular Heart Disease During Pregnancy: Outcomes from a Large Integrated Healthcare System

Valvular heart disease (VHD) accounts for significant morbidity and mortality during pregnancy, with limited data to guide cardio-obstetric risks. This is a retrospective cohort study describing maternal, obstetric, and fetal…

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Low Arrhythmic Risk in Individuals With Brugada ECG Pattern and a Negative dST-Tiso Criterion

Aug 8, 2026 by drzezo in CARDIOLOGY Comments Off on Low Arrhythmic Risk in Individuals With Brugada ECG Pattern and a Negative dST-Tiso Criterion

Risk stratification in individuals with Brugada electrocardiographic pattern (BrECG) remains challenging. The dST-Tiso ECG criterion, defined as an interval between the onset of coved ST-segment elevation and its return to…

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