Inflammatory Peripheral Arterial Aneurysms
Group I Group II Group III Patients 9 5 4 Clinic Age 63.4 62.2 70.7 Males (%) 88.8 60 100 Smoking (%) 77.7 80 75 Diabetes (%) 22.2 40…
CARDIAC SURGERY
Arterial Wall Remodeling and Restenosis Following Vascular Reconstruction
Location Procedure Restenosis (%) References Coronary PTA 21–55 [1–3] Coronary BMS 16–44 [1–3] Coronary DES 10 [4–11] Coronary Atherectomy 27–39 [12, 13] Renal PTA 26–100 [14] Renal BMS 17–60 [14–16]…
Hypoxic Preconditioning of Cardiac Progenitor Cells for Ischemic Heart
Fig. 51.1 Mechanisms that regulate CSPC migration (a), differentiation (b), and proliferation (c). CXCR4 C-X-C chemokine receptor type 4, SDF-1 stromal cell-derived factor-1, sVCAM soluble vascular cell adhesion molecules, SCF…
Nutritional Factors, Oxidative Stress and Lung Transplantation
Fig. 48.1 Oxidative stress Physiological levels of free radicals are essential for cell differentiation, cell growth, cell apoptosis, and immunity against invading microorganisms [21–23]. However, when these free radicals overwhelm…
Neurohormonal Factors in Pediatric Heart Surgery
Effects of sympathetic stimulation Cellular effects Heart Increased cardiomyocyte calcium entry Increased contractility (inotropy) Myocardial hypertrophy Increased heart rate Gene expression: Increased wall stress Increased expression of fetal genes Decreased…
Mechanical Unloading and Heart Remodeling Features
Hypertrophy Contractile dysfunction Calcium cycling Cytoskeletal proteins (sarcomeric, non-sarcomeric, membrane) Beta-adrenergic signaling Metabolism and bioenergetics Myocyte death (apoptosis, autophagy, stress) Endothelium and microvasculature Sympathetic innervation Circulating neurohormones, cytokines Cardiac Hypertrophy…
Cytokine Profiles in Cardiac Diseases and Marrow Stromal Cells Therapy
Edmo Atique Gabriel and Sthefano Atique Gabriel (eds.)Inflammatory Response in Cardiovascular Surgery201310.1007/978-1-4471-4429-8_50© Springer-Verlag London 2013 50. Cytokine Profiles in Cardiac Diseases and Marrow Stromal Cells Therapy Nasser Alkhamees1, Alice Le Huu1 and Dominique Shum-Tim2, 3, 4 (1) Divisions of…
Role of BNP in Pediatric Heart Transplantation
Edmo Atique Gabriel and Sthefano Atique Gabriel (eds.)Inflammatory Response in Cardiovascular Surgery201310.1007/978-1-4471-4429-8_47© Springer-Verlag London 2013 47. Role of BNP in Pediatric Heart Transplantation Marcelo Biscegli Jatene1 and Estela Azeka2 (1) Pediatric Cardiothoracic Surgery Unit, Heart Institute (InCor), University…
Platelet Activation After Lung Transplantation
29. Palabrica T, Lobb R, Furie BC, Aronivitz M, Benjamin C, Hsu Y-M, et al. Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets. Nature….
Cytokine Profile in Heart Transplantation
Fig. 45.1 Immature dendritic cells mature into antigen-presenting cells (APCs) within recipients’ lymph nodes and spleen. APCs present donor alloantigens on their class II MHC molecules. CD4 helper T cells…
