Characteristics and management of outpatients with history of or current atrial fibrillation: The observational French EPHA study

Jul 17, 2017 by in CARDIOLOGY Comments Off on Characteristics and management of outpatients with history of or current atrial fibrillation: The observational French EPHA study

Summary Background Limited French data are available for the different clinical types (paroxysmal, persistent and permanent) of atrial fibrillation and their comorbidities (AF). Aims To provide contemporary insights into the…

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Evidence-based pharmacotherapy after myocardial infarction in France: Adherence-associated factors and relationship with 30-month mortality and rehospitalization

Jul 17, 2017 by in CARDIOLOGY Comments Off on Evidence-based pharmacotherapy after myocardial infarction in France: Adherence-associated factors and relationship with 30-month mortality and rehospitalization

Summary Background International guidelines recommend long-term use of evidence-based treatment (EBT) combining beta-blockers, aspirin/clopidogrel, statins and either angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ACEIs/ARBs) after a myocardial infarction (MI),…

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Distribution of left ventricular ejection fraction and heart rate values in a cohort of stable coronary patients: The INDYCE registry

Jul 17, 2017 by in CARDIOLOGY Comments Off on Distribution of left ventricular ejection fraction and heart rate values in a cohort of stable coronary patients: The INDYCE registry

Summary Background The distribution of left ventricular ejection fraction (LVEF) – a key factor in coronary artery disease (CAD) patient management and prognostication – is poorly documented. Objective To determine LVEF and…

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Clopidogrel resistance: What’s new?

Jul 17, 2017 by in CARDIOLOGY Comments Off on Clopidogrel resistance: What’s new?

Summary The concept of clopidogrel resistance emerged several years ago. Since then, many studies have been performed to elucidate the mechanisms and potential clinical impact of this biological finding. These…

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Anomalous origin of the pulmonary artery from the ascending aorta in a neonate, assessed by two-dimensional echocardiography

Jul 17, 2017 by in CARDIOLOGY Comments Off on Anomalous origin of the pulmonary artery from the ascending aorta in a neonate, assessed by two-dimensional echocardiography

A full-term baby presented at 2 weeks of life with severe congestive heart failure. On clinical examination a 2/6 holosystolic murmur was found, bounding femoral pulses and hepatomegaly. Echocardiography found…

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Metastatic carcinoid tumour of the heart

Jul 17, 2017 by in CARDIOLOGY Comments Off on Metastatic carcinoid tumour of the heart

A 68-year-old woman presenting with metastatic carcinoid tumours of the liver and pancreas was referred for CMR imaging because of LV location on somatostatin receptor scintigraphy imaging, a specific test…

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A case of curable pulmonary hypertension

Jul 17, 2017 by in CARDIOLOGY Comments Off on A case of curable pulmonary hypertension

A 16-year-old girl was admitted for breathlessness. Her only medical history was asthma treated with a bronchodilator and steroids. Examination revealed hepatomegaly, lower limb oedema and a soft systolic murmur…

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Gene therapy for heart failure

Jul 17, 2017 by in CARDIOLOGY Comments Off on Gene therapy for heart failure

Summary Despite the progress achieved in conventional treatment modalities, heart failure remains a major cause of mortality and morbidity. The identification of novel signaling pathways has provided a solid scientific…

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Update on gene therapy for myocardial ischaemia and left ventricular systolic dysfunction or heart failure

Jul 17, 2017 by in CARDIOLOGY Comments Off on Update on gene therapy for myocardial ischaemia and left ventricular systolic dysfunction or heart failure

Summary Despite considerable advances in pharmacological, surgical and technology-based cardiovascular therapy, left ventricular dysfunction and heart failure are increasingly prevalent health problems. Recent studies suggest that angiogenic gene therapy can…

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