Background Transapical aortic valve implantation is a novel therapeutic approach in high-risk patients with severe aortic stenosis. We report a single-center experience during and after the learning curve for establishing…
Background Atrioventricular (AV) conduction abnormalities including complete heart block (CHB) following transcatheter aortic valve implantation (TAVI) are highly variable. The extent to which balloon aortic valvuloplasty (BAV) predilatation contributes to…
Background Severe aortic regurgitation (AR) is a contraindication for aortic balloon valvuloplasty (ABV). However, the effects of ABV in the presence of mild and moderate AR are unknown. Methods A…
Background Routine use of glycoprotein IIb/IIIa inhibitors (GPI) reduces ischemic events during PCI, but this benefit appears to be negated by excessive bleeding complication and thrombocytopenia and did not translate…
Background Thrombolytic therapy is still used for patients presenting with ST-elevation myocardial infarction. The safety and efficacy of bivalirudin (BIV) for primary percutaneous coronary intervention (PCI) in these patients have…
Background Severe aortic stenosis (AS) patients with left ventricular ejection fraction (LVEF) <20% are currently excluded from transcatheter aortic valve implant trials and are believed to be at higher risk…
Introduction Pivotal ranolazine trials did not include patients with refractory angina on optimal antianginal medications. The purpose of this study was to evaluate the efficacy and safety of ranolazine for…
Aim Our prospective in this study to test whether increase in the clopidogrel maintenance dose results in increased platelet inhibition that may be reflected in decreasing major adverse cardiac effects…
Background Late DES thrombosis has emerged as an important issue. At present, light transmission aggregometry (LTA) remains the gold standard for determining adequate platelet inhibition for DES patients on clopidogrel….
Background VEGF is a key regulator of angiogenesis. It is thought to be implicated in the pathogenesis of atherosclerotic plaque neovascularization and thus promotes its infiltration by inflammatory cells with…
