Interaction of Risk of Death and Improvement in Functional Capacity After Cardiac Rehabilitation on Heart Failure Prognosis

Jun 16, 2026 by in CARDIOLOGY Comments Off on Interaction of Risk of Death and Improvement in Functional Capacity After Cardiac Rehabilitation on Heart Failure Prognosis
Abstract Whether risk of death interacts with change in 6-minute walking test (6MWT) distance after cardiac rehabilitation (CR) on heart failure (HF) prognosis is unknown. We studied 1,569 patients with…
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Incidence and Predictors of Atrial Fibrillation After Cavotricuspid Isthmus Ablation for Typical Atrial Flutter

Jun 16, 2026 by in CARDIOLOGY Comments Off on Incidence and Predictors of Atrial Fibrillation After Cavotricuspid Isthmus Ablation for Typical Atrial Flutter
Cavotricuspid isthmus (CTI) ablation is a highly effective treatment of typical atrial flutter (AFL). The emergence of new-onset atrial fibrillation (AF) following CTI ablation is clinically relevant but limited data…
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A Phase 1b Randomized Clinical Trial of AZD5462 and Dapagliflozin in Patients with Heart Failure and Moderate Renal Impairment

Jun 16, 2026 by in CARDIOLOGY Comments Off on A Phase 1b Randomized Clinical Trial of AZD5462 and Dapagliflozin in Patients with Heart Failure and Moderate Renal Impairment
AZD5462 is the first oral selective relaxin/insulin-like family peptide receptor 1 agonist in clinical development. The aim of this mechanistic study is to investigate the renal effects of AZD5462 when…
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Systemic Review of Inflammatory Pathways and Immune Modulation in Atherosclerotic Cardiovascular Disease

Jun 16, 2026 by in CARDIOLOGY Comments Off on Systemic Review of Inflammatory Pathways and Immune Modulation in Atherosclerotic Cardiovascular Disease
Abstract Inflammation is a central contributor to atherosclerotic cardiovascular disease (ASCVD), and targeted immune modulation may provide added benefit beyond lipid-lowering. We conducted a systematic review (PRISMA 2020–compliant) of 57…
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The Obesity Paradox in Chronic Total Occlusion Percutaneous Coronary Intervention: Contemporary Outcomes Across Body Mass Index Categories

Jun 16, 2026 by in CARDIOLOGY Comments Off on The Obesity Paradox in Chronic Total Occlusion Percutaneous Coronary Intervention: Contemporary Outcomes Across Body Mass Index Categories
This study examined the impact of body mass index (BMI) on procedural and long-term outcomes following percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). While obesity is an established…
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Identifying Pathogenesis of Acute Coronary Syndromes using Sequence Contrastive Learning in Coronary Angiography

Jun 16, 2026 by in CARDIOLOGY Comments Off on Identifying Pathogenesis of Acute Coronary Syndromes using Sequence Contrastive Learning in Coronary Angiography
Advances in intracoronary imaging have made it possible to distinguish different pathological mechanisms underlying acute coronary syndrome (ACS) in vivo. Accurate identification of these mechanisms is increasingly recognized as essential…
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Identifying Pathogenesis of Acute Coronary Syndromes using Sequence Contrastive Learning in Coronary Angiography

Jun 16, 2026 by in CARDIOLOGY Comments Off on Identifying Pathogenesis of Acute Coronary Syndromes using Sequence Contrastive Learning in Coronary Angiography
Advances in intracoronary imaging have made it possible to distinguish different pathological mechanisms underlying acute coronary syndrome (ACS) in vivo. Accurate identification of these mechanisms is increasingly recognized as essential…
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Mini-Crush Versus Double Kissing Crush in Bifurcation Percutaneous Coronary Intervention: Insights From PROGRESS-BIFURCATION Registry

Jun 16, 2026 by in CARDIOLOGY Comments Off on Mini-Crush Versus Double Kissing Crush in Bifurcation Percutaneous Coronary Intervention: Insights From PROGRESS-BIFURCATION Registry
There are limited data on the use of the mini-crush technique in 2-stent bifurcation percutaneous coronary intervention (PCI). Observational, multicenter (n = 7), international cohort study between 2013 and 2025,…
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