Introduction A non–ST-elevation acute coronary syndrome (NSTE-ACS) is caused by a severe flow-limiting stenosis or acute thrombotic obstruction of a coronary artery (see Chapter 13 ). In the absolute majority…
Introduction Atherosclerotic plaque rupture followed by arterial thrombosis is the major determinant that leads to an acute coronary syndrome (ACS). Platelet adhesion, activation, and aggregation have a pivotal role in…
Introduction Myocardial infarction (MI) includes patients presenting with ST-elevation MI (STEMI) and those without ST-segment MI (NSTEMI), and although these types of MI share a common physiopathology and principles of…
Case Vignette A 56-year-old riverboat captain experienced sudden onset of shortness of breath and diaphoresis at 1:30 am while on his boat near Red Wing, Minnesota ( Figure 5-e1 )….
Case Presentation A 57-year-old man presents to a community hospital without capability for primary percutaneous coronary intervention (PPCI) in the early morning (4 am ) with a 1.5-hour history of…
Introduction Cardiac troponin (cTn) is the preferred biomarker for the evaluation of patients with suspected acute myocardial infarction (MI) (see Chapter 7 ). In addition, it makes sense that other…
Introduction Acute myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide (see Chapter 2 ). Although an estimated 157,000 patients will die each year in the United…
Introduction The key principles that underlie management of myocardial infarction (MI) are based on the pathophysiology of the condition and the time course of irreversible myocardial injury. The fundamental goals…
Introduction Previous chapters have detailed the important roles of clinical presentation (see Chapter 6 ), cardiovascular risk factors, electrocardiography (ECG), and biomarkers (see Chapter 7 and Chapter 8 ) in…
Introduction A ST-segment myocardial infarction (STEMI) is caused by the occlusion of a major epicardial coronary artery and is generally triggered by rupture of a vulnerable plaque, with subsequent formation…
