Outline Assessment of Human Sympathetic and Parasympathetic Nervous System Activity, 181 Catecholamines, 181 Microneurography, 182 Arterial Baroreflex Sensitivity, 183 Heart Rate Variability, 183 Cross-Spectral Analysis, 184 Tracer Imaging With Catecholamine…
Outline Left Ventricular Remodeling, 166 Alterations in the Biology of the Cardiac Myocyte, 166 Alterations in the Myocardium, 169 Changes in Left Ventricular Geometry, 170 Clinical Studies Linking Left Ventricular…
Outline What Is Human Immunodeficiency Virus-Associated Heart Failure?, 395 Historical Perspective, 395 Contemporary Shifts in Epidemiology, 396 Pathophysiology of Heart Failure in Human Immunodeficiency Virus, 396 Poor Human Immunodeficiency Viral…
Outline Epidemiology, 301 Natural History, 302 Clinical Features, 303 Misdiagnosis and Obstacles to Early Diagnosis, 303 Raising Clinical Suspicion for Cardiac Amyloidosis, 303 Diagnosis, 303 Electrocardiography, 303 Laboratory Testing, 303…
Outline Epidemiology of Chronic Kidney Disease and the Impact on Heart Failure, 214 Worsening Kidney Function and Prognosis, 214 Pathophysiology of Chronic Kidney Disease in Heart Failure, 215 Peripheral Volume…
Outline Patient Characteristics, 244 Demographic Distribution, 244 Comorbidities, 245 Prevalence and Incidence, 245 Estimates and Trends, 245 Impact of Demographics and Socioeconomic Status, 246 Age, 246 Sex, 246 Race, 246…
Outline Skeletal Muscle Adaptations in Heart Failure, 222 Skeletal Muscle Atrophy, 223 Skeletal Muscle Protein Synthesis and Reduced Anabolic Hormones/Effectors, 223 Skeletal Muscle Protein Breakdown and Increased Catabolic Hormones/Effectors, 224…
Outline Overview of Cardiac Metabolism, 233 Hallmarks and Regulation of Cardiac Energy Metabolism, 233 Crosstalk Between Cardiac Metabolism and Signaling, 235 Significance of Cardiac Energetics for Heart Disease, 235 Metabolic…
Outline Pathophysiologic Insights, 201 Endothelial Dysfunction in Clinical Heart Failure, 203 Endothelial Dysfunction of the Coronary Circulation in Heart Failure, 203 Systemic Nature of Endothelial Dysfunction in Heart Failure, 204…
Outline The Postnatal Heart is Not a Postmitotic Organ, 43 Sources of Controversy in Postnatal Mammalian Cardiomyocyte Proliferation 44 Evidence of Cardiomyocyte Turnover in the Adult Heart, 44 Molecular Basis…
