Primary and Secondary Prevention of Lung Cancer
Tobacco dependence is the most consequential target to reduce the burden of lung cancer worldwide. Quitting after a cancer diagnosis can improve cancer prognosis, overall health, and quality of life….
Pulmonary Complications of Immunotherapy
Immune checkpoint inhibitor (ICI) therapy represents a paradigm shift in the treatment of patients with locally advanced and metastatic lung cancer. Although immunotherapy generally has a more favorable safety profile…
Management of Malignant Pleural Effusions
Malignant pleural effusion frequently complicates both solid and hematologic malignancies and is associated with high morbidity, mortality, and health care costs. Although no pleura-specific therapy is known to impact survival,…
Advances in Treatment of Locally Advanced or Metastatic Non–Small Cell Lung Cancer
The treatment of metastatic non–small cell lung cancer (NSCLC) is constantly evolving. Although the advent of immunotherapy has played an important role in the treatment of patients with NSCLC, the…
Management of Oligometastatic Disease in Advanced Non–Small Cell Lung Cancer
Non–small cell lung cancer with very limited extent of metastatic spread commonly is termed, oligometastatic disease ( OMD ), and typically described as no more than 3 to 5 lesions….
Palliative Care in Lung Cancer
There is growing evidence that palliative care supports the needs of patients with advanced lung cancer. Early palliative care referral has been shown to improve quality of life, decrease symptom…
Advances in the Treatment of Non–Small Cell Lung Cancer
Clinical development of immune checkpoint blockade has dramatically changed the treatment paradigm and prognosis for patients with non–small cell lung cancer. Immune checkpoint blockade with PD-1 and PD-L1 antibodies generates…
Breaking the Impasse
Small cell lung cancer (SCLC) is an aggressive malignancy and carries a poor prognosis with limited effective treatments in the advanced setting. SCLC is characterized by a high tumor mutation…
Alternatives to Surgery for Early-Stage Non–Small Cell Lung Cancer
Thermal ablation involves the application of heat or cold energy to the lung under image guidance to eradicate tumors. It is indicated for treatment of early-stage non–small cell lung cancer…
Lung Cancer Staging
Anatomic staging is a critical step in evaluation of patients with lung cancer. Accurate identification of stage based on features of primary tumor (T), regional nodes (N), and metastatic disease…
