Panlobular Emphysema
Panlobular Emphysema Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. General Features Panlobular emphysema is characterized by uniform destruction of the pulmonary acinus. This is in contrast to the centriacinar…
Paraseptal and Interstitial Emphysema
Paraseptal and Interstitial Emphysema Marie-Christine Aubry, M.D. Allen P. Burke, M.D. Paraseptal Emphysema Definition Paraseptal (distal acinar) emphysema is the third major subtype of emphysema, after centrilobular (Chapter 44) and…
Centrilobular Emphysema
Centrilobular Emphysema Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. General Features Emphysema, along with chronic bronchitis, is in a category of disease known collectively as chronic obstructive pulmonary disease….
Pulmonary Parasitic Infections
Pulmonary Parasitic Infections Bobbi S. Pritt, M.D., MSc Overview A number of parasites may be found in the human lung, including unicellular protozoa, helminths (worms), and, rarely, arthropods.1,2,3,4,5 The types…
Pneumocystis Pneumonia
Pneumocystis Pneumonia Allen P. Burke, M.D. Background Pneumocystis organisms were first described in rats and guinea pigs in the early 20th century as protozoa related to trypanosomes (reviewed by Catherinot…
Fungal Infections
Fungal Infections Brandon T. Larsen, M.D., Ph.D. Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. General Fungi are eukaryotic organisms that are found ubiquitously in the natural environment. Of…
Pulmonary Tuberculosis and Atypical Mycobacterial Infection
Pulmonary Tuberculosis and Atypical Mycobacterial Infection Fabio R. Tavora, M.D., Ph.D. Allen P. Burke, M.D. Mycobacterium Tuberculosis Microbiology Tuberculosis has been known as a human disease for several millennia. It…
Viral Pneumonias
Viral Pneumonias Allen P. Burke, M.D. Marie-Christine Aubry, M.D. Overview Viral Pneumonias in Immunocompetent Patients Viral infections account for 5% to 34% of community-acquired pneumonias.1 Because many cases of community-acquired…
Bacterial Pneumonias
Bacterial Pneumonias Allen P. Burke, M.D. Marie-Christine Aubry, M.D. Community-Acquired Pneumonia Clinical Findings Pneumonia is the most common cause of death from infectious diseases worldwide. Community-acquired pneumonia is believed to…
Constrictive Bronchiolitis
Constrictive Bronchiolitis Fabio R. Tavora, M.D., Ph.D. Allen P. Burke, M.D. Historical Background Constrictive (obliterative) bronchiolitis is a clinicopathologic entity of diverse causes denoting inflammation and fibrosis of bronchioles, usually…
