Cardiac Disease in Endocrine Disorders
Cardiac Disease in Endocrine Disorders Allen P. Burke, M.D. Adina Paulk, M.D. Introduction The effect of metabolism and endocrine disorders on the heart is multifaceted, and there are no specific…
Cor Pulmonale
Cor Pulmonale Allen P. Burke, M.D. Adina Paulk, M.D. Definition Cor pulmonale, or pulmonary heart disease, is right ventricular enlargement with or without right heart failure resulting from pulmonary hypertension…
Left Ventricular Hypertrophy and Failure
Left Ventricular Hypertrophy and Failure Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Left Ventricular Hypertrophy Physiology and Causes Cardiac hypertrophy is an adaptive response to an increased load (pressure…
Pathology of Cardiac Devices and Interventions
Pathology of Cardiac Devices and Interventions Joseph J. Maleszewski, M.D. Allen P. Burke, M.D. Introduction Open and percutaneous interventions performed on the heart and thoracic aorta are relatively commonplace. They…
Congenital Heart Disease
Congenital Heart Disease Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. General Epidemiology Congenital abnormalities of the heart and aortic arch (excluding the congenitally bicuspid aortic valve) occur in slightly…
Sudden Cardiac Death
Sudden Cardiac Death Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Definition Sudden cardiac death (SCD) is an unexpected death due to cardiac causes occurring in a short time period…
Myocardial Response to Injury
Myocardial Response to Injury Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. General Myocyte injury results from a variety of insults, including ischemia, inflammation, toxic insults, and physical forces…
Examination of Cardiovascular Specimens
Examination of Cardiovascular Specimens Joseph J. Maleszewski, M.D. Allen P. Burke, M.D. Overview Cardiac specimens may be procured for examination either at autopsy or surgery. Autopsy-derived specimens are in the…
Miscellaneous Mediastinal Tumors (Paraganglioma, Vascular and Lipomatous Tumors, Other Sarcomas)
Miscellaneous Mediastinal Tumors (Paraganglioma, Vascular and Lipomatous Tumors, Other Sarcomas) Borislav A. Alexiev, M.D. Jennifer M. Boland, M.D. Paraganglioma Terminology Paragangliomas are neuroendocrine tumors that arise in the extraadrenal sympathetic…
Synovial Sarcoma
Synovial Sarcoma Borislav A. Alexiev, M.D. Jennifer M. Boland, M.D. Allen P. Burke, M.D. Terminology Synovial sarcoma is a malignant mesenchymal tumor that displays a variable degree of epithelial differentiation,…
