Nonatherosclerotic Coronary Artery Disease Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. Congenital Anomalies of Coronary Circulation Overview Congenital anomalies of the origin and course of coronary arteries are…
Coronary Artery Bypass Grafts Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. Clinical Incidence and Indications Coronary artery bypass graft surgery is performed 350,000 times annually in the United…
Coronary Stents Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Introduction Percutaneous balloon angioplasty with stenting has become standard treatment for obstructive coronary artery disease, including patients who present with…
Chronic Ischemic Heart Disease Allen P. Burke, M.D. Joseph J. Maleszewski, M.D. Background and Terminology “Ischemic cardiomyopathy” denotes the presence of obstructive epicardial coronary atherosclerosis with decreased left ventricular systolic…
Myocardial Infarction Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. Types of Acute Infarcts Acute myocardial infarction indicates irreversible myocardial injury resulting in coagulative necrosis of the myocardium. Ischemia…
Coronary Atherosclerosis Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. Methods of Sampling The practicing pathologist will encounter coronary atherosclerosis primarily at autopsy. Because of the high prevalence of…
Cardiac Sarcoidosis Fabio R. Tavora, M.D., Ph.D. Allen P. Burke, M.D. Epidemiology The prevalence of sarcoidosis is difficult to ascertain, because many patients are asymptomatic, and the clinical symptoms and…
Cardiac Amyloidosis Joseph J. Maleszewski, M.D. Allen P. Burke, M.D. Introduction General Amyloidosis is the deposition of misfolded protein with an antiparallel β-pleated sheet configuration in a variety of organs…
Cardiac Involvement in Rheumatologic Diseases Allen P. Burke, M.D. Fabio R. Tavora, M.D., Ph.D. Acute Rheumatic Carditis Incidence and Epidemiology Acute rheumatic carditis is a common sequela of acute rheumatic…
Cardiac Disease in Hematologic Disorders Allen P. Burke, M.D. Adina Paulk, M.D. Sickle Cell Disease Sickle cell disease is a chronic hemolytic anemia caused by abnormal hemoglobin that polymerizes and…
