Preoperative Chemotherapy/Radiation Therapy for Early Stage and Locally Advanced Non-Small Cell Lung Carcinoma Brian E. Lally Harvey I. Pass Kathy S. Albain Surgery remains the cornerstone of management for patients…
Preoperative Chemotherapy for Early Stage Non-Small Cell Lung Cancer Jan P. van Meerbeeck Katherine M. Pisters BACKGROUND Surgery remains the cornerstone of treatment for patients with early stage non-small cell…
Targeted Therapies and Radiation in Lung Cancer David Raben Amanda Schwer Paul Van Houtte The use of targeted drugs—those that attempt to render specific aspects of the cancer cell-signaling pathway…
Lung Cancer Vaccines Nevin Murray Robert Eager John Nemunaitis Anecdotal observations of spontaneous regression of tumors in patients with cancer provided the initial evidence of the presence of an inborn…
Other Signal Transduction Agents Alex A. Adjei Cancer represents a multitude of diseases characterized by uncontrolled cellular proliferation and is the second most common cause of death in Western society.1…
Anti-EGFR Therapies: How to Select Patients Fred R. Hirsch Tetsuya Mitsudomi Pasi A. Jänne Epidermal growth factor receptor (EGFR) inhibitors have proven effective in some patients with advanced non-small cell…
Antiangiogenic Agents Christian Manegold Leora Horn Alan Sandler ROLE OF ANGIOGENESIS IN SOLID TUMORS Tumor development is a multistep and complex process, requiring the transformation of a normal cell into…
Chemotherapy for Recurrent or Refractory Advanced Non-Small Cell Lung Cancer Peter M. Ellis Frances A. Shepherd Publication of the Non-Small Cell Lung Cancer (NSCLC) Collaborative Group metaanalysis in 1995 established…
Pharmacogenomics in Lung Cancer: Predictive Biomarkers for Chemotherapy Oliver Gautschi Philip C. Mack David R. Gandara Rafael Rosell Commonly used platinum-based chemotherapy regimens have shown comparable activity in randomized studies…
Chemotherapy for Advanced Non-Small Cell Lung Cancer Leora Horn Cesare Gridelli Corey Langer David H. Johnson Lung cancer is the leading cause of cancer-related mortality worldwide.1,2 In North America and…
