Objective Heart Failure comprises huge medical attention causing distinctive mortality and morbidity especially in westernized societies with a great impact on health care envisioning. The present study aimed to evaluate…
Objective Herein, we studied the functional interaction between 5-HT2B receptor blocker (SB-204741) and GSK-3β inhibitor (SB-216763) in myocardial-ischemia reperfusion injury in rats. Methods To evaluate this hypothesis, either SB-204741 or…
Objectives The present study was designed to investigate the cardioprotective effect of sodium nitrite (NaNO2) and sodium nitrate (NaNO3) against myocardial ischemia-reperfusion (I/R) injury in a pig regional ischemia model….
Objective Oxidative stress has a prominent role in the cathecolamine induced cardiac damage. The aim of this study is to investigate whether resveratrol (RVT) ameliorates isoproterenol (ISO) induced myocardial damage…
Background Intermedin/Adrenomedullin 2 (IMD/AM2) is a novel peptide related to the calcitonin gene-related peptide family. It is a vascular regulatory factor of homeostasis and a vital endogenous protective factor against…
Introduction Pulmonary artery hypertension is devastating disease that has very serious outcomes. Dysregulated angiogenesis is one of the main responsible courses in pathophysiology of disease. Our experimental research intends to…
Background N-acetylcysteine, beta-glucan, and coenzyme Q10 have been shown to have antioxidant and anti-inflammatory effects on reperfusion injury. The aim of our study was to determine and evaluate the effects…
Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Many factors and substances may stimulate angiogenesis and exhibit proliferative effect. In this study, we aimed to investigate the…
Aim Recently bone marrow or peripheral blood derived stem cell therapy has been used in many fields of clinical medicine. In patients with peripheral vascular disease in whom limb salvage…
The clinical course of care is a useful / essential for the orientation of clinical practice guidelines compared internationally, involving all the workers involved in the process. The objective of…
