Objective The purpose of this study was to reveal independent predictors of unfavorable course of active native valve infective endocarditis (ANVIE) and to determine impact of the surgery and its…
Subject The measurement of malcoaptation Surface Area assessed by trans-esophageal echocardiography has been introduced to differentiate severity of Aortic regurgitation(AR), but its value has not been accurately determined. The present…
Objective The role of systemic and chronic inflammatory processes in the pathophysiology of rheumatic heart valve disease is well-known. Neutrophil to lymphocyte ratio (NLR) was shown to be an indicator…
Objective Mitral valve prolapse (MVP) affects 2-4% of the general population and remains one of the most frequent indications for valvular surgery. Previous familial and pathophysiological studies suggest a complex…
Objectives Inflammation and oxidative stress play an important role in the pathogenesis of heart valve diseases (especially rheumatic valves). It is also known that matrix metalloproteinase is associated with myxomatous…
Pathophysiological processes that initiate calcific aortic stenosis are still undefined and there are no currently available treatments that effect disease progression. The aim of this study was to evaluate pathologically,…
Background Coronary artery ectasia (CAE) has been established as a localized or diffuse non-obstructive lesion of the epicardial coronary arteries. Atherosclerosis plays an important role the etiopathogenesis of CAE. Inflammation…
Objective Previous studies showed that both inflammation and platelets have had a role in slow coronary flow (SCF) development. Platelet-to-lymphocyte ratio (PLR) as an emerging inflammatory indicator was significantly associated…
Background Rheumatic fever (RF) still remained the most common cause of acquired heart disease in children and young adults. Permanent damage to the hearts valves after RF requires medical or…
Background Atherosclerosis plays an important role in the formation of saphenous vein graft disease. Previous trials showed that inflammatory blood cells has an active role in this process. The platelet…
