Objectives Inflammation and oxidative stress play an important role in the pathogenesis of heart valve diseases (especially rheumatic valves). It is also known that matrix metalloproteinase is associated with myxomatous…
Pathophysiological processes that initiate calcific aortic stenosis are still undefined and there are no currently available treatments that effect disease progression. The aim of this study was to evaluate pathologically,…
Background Coronary artery ectasia (CAE) has been established as a localized or diffuse non-obstructive lesion of the epicardial coronary arteries. Atherosclerosis plays an important role the etiopathogenesis of CAE. Inflammation…
Objective Previous studies showed that both inflammation and platelets have had a role in slow coronary flow (SCF) development. Platelet-to-lymphocyte ratio (PLR) as an emerging inflammatory indicator was significantly associated…
Background Rheumatic fever (RF) still remained the most common cause of acquired heart disease in children and young adults. Permanent damage to the hearts valves after RF requires medical or…
Background Atherosclerosis plays an important role in the formation of saphenous vein graft disease. Previous trials showed that inflammatory blood cells has an active role in this process. The platelet…
Introduction Heart murmurs in children are the most common reason for specialist cardiac treatment. Evaluation of heart murmur represents exclusion or existence of congenital anomalies of the heart. Normal anatomical…
Aim In this study, we aimed to investigate the association between Thymidine 786 Cytosine polymorphism of endothelial nitric oxide (eNOS) gene and coronary collateral circulation (CCC). Method 286 patients having…
Introduction Myocardial bridge(MB) is a rare congenital disease with a relatively good prognosis. It has been associated with unstable angina, myocardial infarction and sudden cardiac death in the literature. In…
Objectives The cardiac syndrome X (CSX) is characterized by microvascular dysfunction which associated with oxidative stress. Thiols are mainly responsible for the intracellular antioxidant status. They are sulfur analogs of…
