Congenital aortic stenosis is a condition with implications of multiple interventions over a lifetime. We therefore read with interest the report by Maskatia et al reporting their 25-year single-institutional experience…
We read with interest the timely report by Devinsky, who reviewed the published research on sudden unexpected death in epilepsy. The investigator suggested the importance of pacemaker insertion in documented…
Idiopathic pulmonary arterial hypertension (PAH) is usually associated with a poor outcome but the prognosis with other forms of PAH is not well-described. Advances in therapy have furthered clouded the…
In patients with hypertrophic cardiomyopathy, metabolic stress testing has been shown to quantify disease limitations, to differentiate between hypertrophic cardiomyopathy and athletic hearts, and has shed light on the determinants…
D-dimer, microparticles, and p-selectin are venous thrombotic risk markers. Elevated p-selectin is associated with increased cardiovascular events. We examined the effects of exercise and air travel on the markers of…
Pulmonary arterial hypertension (PAH) is a disorder in which pulmonary arterial remodeling and vasoconstriction progressively lead to right heart failure (HF), exercise intolerance, and high mortality. Beta-blockers have been shown…
Although stenting has been used as a treatment option for aortic coarctation (CoA) at increasingly younger ages, limited information is available on the long-term follow-up of stent implantation for CoA…
The aim of this study was to evaluate the role of left ventricular (LV) dysfunction (global and regional, systolic and diastolic) acute dyssynchrony, ischemic mitral regurgitation (MR), and afterload changes…
We sought to determine whether depressed myocardial contraction fraction (MCF; ratio of left ventricular [LV] stroke volume to myocardial volume) predicts cardiovascular disease (CVD) events in initially healthy adults. A…
Patients with obstructive hypertrophic cardiomyopathy (HC) are at increased risk of death or severe symptoms. Although metabolic exercise testing is routinely used in the evaluation of a variety of cardiac…
